Name: Cytotoxin 2 Protein, Naja atra, Recombinant (His & Myc)
Brand: TargetMol
SKU: TMPH-03036
Rating: 4.5 (1 reviews)

规格

价格

库存

数量

5 μg

¥ 825

20日内发货

10 μg

¥ 1,360

20日内发货

20 μg

¥ 2,290

20日内发货

50 μg

¥ 3,460

20日内发货

100 μg

¥ 4,750

20日内发货

200 μg

¥ 6,830

20日内发货

500 μg

¥ 10,800

20日内发货

1 mg

¥ 16,000

20日内发货

生物活性

产品描述	Basic protein that binds to cell membrane and depolarizes cardiomyocytes. It also shows lytic activities, but 2-fold less important than that of CTX-A4. It binds to the integrin alpha-V/beta-3 (ITGAV/ITGB3) with a moderate affinity. It may interact with sulfatides in the cell membrane which induces pore formation and cell internalization and is responsible for cytotoxicity in cardiomyocytes. It also may target the mitochondrial membrane and induce mitochondrial swelling and fragmentation.
生物活性	Activity has not been tested. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
研究背景	Basic protein that binds to cell membrane and depolarizes cardiomyocytes. It also shows lytic activities, but 2-fold less important than that of CTX-A4. It binds to the integrin alpha-V/beta-3 (ITGAV/ITGB3) with a moderate affinity. It may interact with sulfatides in the cell membrane which induces pore formation and cell internalization and is responsible for cytotoxicity in cardiomyocytes. It also may target the mitochondrial membrane and induce mitochondrial swelling and fragmentation.
种属	Naja atra
表达系统	E. coli
标签	N-10xHis, C-Myc
蛋白编号	P01442
氨基酸序列	LKCNKLVPLFYKTCPAGKNLCYKMFMVSNLTVPVKRGCIDVCPKNSALVKYVCCNTDRCN
蛋白构建	22-81 aa
蛋白纯度	> 85% as determined by SDS-PAGE.
缓冲液	If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.
复溶方法	Reconstitute the lyophilized protein in sterile deionized water. The product concentration should not be less than 100 μg/mL. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
别名	Cytotoxin 2, Cardiotoxin II, Cardiotoxin analog II, Cardiotoxin A2 (CTX A2), Cardiotoxin 2 (CTX-2), Cardiotoxin 1A
内毒素	< 1.0 EU/μg of the protein as determined by the LAL method.

化学信息

分子量	14.2 kDa (predicted)

储存&溶解度

运输方式	In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice.
存储	Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

Cytotoxin 2 Protein, Naja atra, Recombinant (His & Myc)

Cytotoxin 2 Protein, Naja atra, Recombinant (His & Myc)

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