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顶部生物活性储存和溶解信息计算器

Anti-IL-17RA Antibody-APC (7E127)

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产品编号 TMAY-01300A

别名 interleukin 17 receptor A, IL-17RA, IL17R, hIL-17R, CDw217, CD217, CANDF5

Anti-IL-17RA Antibody-APC (7E127) 是一种 APC-conjugated Mouse 抗体，靶向 IL-17RA。Anti-IL-17RA Antibody-APC (7E127) 可用于 FCM。

Anti-IL-17RA Antibody-APC (7E127)

Anti-IL-17RA Antibody-APC (7E127)

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产品编号 TMAY-01300A 别名 interleukin 17 receptor A, IL-17RA, IL17R, hIL-17R, CDw217, CD217, CANDF5

Anti-IL-17RA Antibody-APC (7E127) 是一种 APC-conjugated Mouse 抗体，靶向 IL-17RA。Anti-IL-17RA Antibody-APC (7E127) 可用于 FCM。

规格价格库存数量
25 T
¥ 885
5日内发货
100 T
¥ 2,790
5日内发货
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产品介绍

生物活性
产品描述
Anti-IL-17RA Antibody-APC (7E127) is a APC-conjugated Mouse antibody targeting IL-17RA. Anti-IL-17RA Antibody-APC (7E127) can be used in FCM.
别名interleukin 17 receptor A, IL-17RA, IL17R, hIL-17R, CDw217, CD217, CANDF5
Ig Type
Mouse IgG1
克隆号
7E127
交叉反应
Human
特异性
Human IL-17RA
验证活性
Flow cytometric analysis of Human IL17RA(CD217) expression on human whole blood granulocytes. Cells were stained with APC-conjugated anti-Human IL17RA(CD217). The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of viable granulocytes.
应用FCM
推荐剂量
5 μl/Test, 0.1 mg/ml
抗体种类
Monoclonal
宿主来源Mouse
构建方式This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human IL17RA/IL-17RA/CD217 (rh IL17RA/IL-17RA/CD217; TMPY-01371; NP_055154.3; Met1-Trp320) and conjugated with APC under optimum conditions, the unreacted APC was removed.
纯化方式Protein A
性状Liquid
缓冲液PBS solution containing 0.5% BSA and 0.03%ProClin300
研究背景Interleukin-17 receptor (IL-17R), also known as Interleukin-17 receptor A (IL-17RA) and CD217 antigen (CD217), is a cytokine receptor that binds interleukin 17. IL-17R/IL-17RA (CD217) is a proinflammatory cytokine secreted by activated T-lymphocytes. It is a potent inducer of the maturation of CD34-positive hematopoietic precursors into neutrophils. IL-17R/IL-17RA (CD217) is a ubiquitous type I membrane glycoprotein that binds with low affinity to interleukin 17A. Interleukin 17A and its receptor IL-17RA play a pathogenic role in many inflammatory and autoimmune diseases such as rheumatoid arthritis. Like other cytokine receptors, this receptor likely has a multimeric structure. Defects in IL-17R/IL-17RA (CD217) are the cause of familial candidiasis type 5 (CANDF5). CANDF5 is a rare disorder with altered immune responses and impaired clearance of fungal infections, selective against Candida. It is characterized by persistent and/or recurrent infections of the skin, nails, and mucous membranes caused by organisms of the genus Candida, mainly Candida albicans.
偶联与修饰
偶联
APC
其他可选修饰符
Unconjugated/FITC/PE
可提供抗体种类
4
抗原信息
免疫原
Recombinant Protein: Human IL17RA/IL-17RA/CD217 Protein (TMPY-01371)
抗原种属
Human
存储&运输
储存方式Store at 2°C-8°C for 12 months, do not freeze. Keep away from direct sunlight.
运输方式Shipping with blue ice.

计算器

  • 稀释 计算器

关键词

CD-217CD 217CANDF-5CANDF 5

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