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顶部生物活性储存和溶解信息计算器

Anti-COL17A1 Antibody (5Q412)

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Anti-COL17A1 Antibody (5Q412)
产品编号 TMAC-00928
别名 Collagen alpha-1(XVII) chain, COL17A1, Bullous pemphigoid antigen 2, BPAG2, BP180, 180 kDa bullous pemphigoid antigen 2

Anti-COL17A1 Antibody (5Q412) 是一种 Rabbit 抗体，靶向 COL17A1。Anti-COL17A1 Antibody (5Q412) 可用于 WB,ICC/IF,IHC,IP。

Anti-COL17A1 Antibody (5Q412)

Anti-COL17A1 Antibody (5Q412)

Rating icon 还可以
Anti-COL17A1 Antibody (5Q412)
产品编号 TMAC-00928 别名 Collagen alpha-1(XVII) chain, COL17A1, Bullous pemphigoid antigen 2, BPAG2, BP180, 180 kDa bullous pemphigoid antigen 2

Anti-COL17A1 Antibody (5Q412) 是一种 Rabbit 抗体，靶向 COL17A1。Anti-COL17A1 Antibody (5Q412) 可用于 WB,ICC/IF,IHC,IP。

规格价格库存数量
50 μL
¥ 1,485
5日内发货
100 μL
¥ 2,490
5日内发货
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产品介绍

生物活性
产品描述
Anti-COL17A1 Antibody (5Q412) is a Rabbit antibody targeting COL17A1. Anti-COL17A1 Antibody (5Q412) can be used in WB,ICC/IF,IHC,IP.
别名Collagen alpha-1(XVII) chain, COL17A1, Bullous pemphigoid antigen 2, BPAG2, BP180, 180 kDa bullous pemphigoid antigen 2
Ig Type
IgG
交叉反应
Human,Mouse,Rat
验证活性
1. Immunohistochemical analysis of paraffin-embedded mouse skin tissue using anti-Collagen XVII antibody. Counter stained with hematoxylin.
2. ICC staining Collagen XVII in HUVEC cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
应用
WB
ICC/IF
IHC
IP
推荐剂量
WB: 1:1000-2000; IHC: 1:50-200; ICC/IF: 1:50-200
抗体种类
Monoclonal
宿主来源Rabbit
构建方式Recombinant Antibody
纯化方式ProA affinity purified
性状Liquid
缓冲液1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
研究背景The extensive collagen family comprises several chain types, including fibril-forming interstitial collagens and basement membrane collagens, with each type containing multiple isoforms. Products of the COL gene family, collagens are characterized as fibrous, extracellular matrix proteins with high tensile strength that constitute the major components of connective tissues, such as tendons and cartilage. All collagens contain a triple helix domain and frequently show lateral self-association in order to form complex connective tissues. Collagen Type XVII, also designated BP180, represents a type II transmembrane, epithelial adhesion molecule that plays a role in cell migration and differentiation. The full length Collagen Type XVII protein is expressed in hemidesmosomes of keratinocytes. Proteolytic shedding of Collagen Type XVII results in a species in the extracellular matrix, and this process may be mediated by a disintegrin and metalloprotease (ADAM) family member. The BPAG2 gene, which encodes the Collagen Type XVII protein, maps to human chromosome 10q25.1. Mutations in this gene result in Bullous pemphigoid, an inflammatory subepidermal blistering skin disease associated with an IgG autoimmune response to Collagen Type XVII.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Protein
Uniprot ID
Q9UMD9
化学信息
分子量Theoretical: 130/180 kDa.
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

计算器

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关键词

Collagen α-1(XVII) chainCollagen a-1(XVII) chainCOL17A 1BPAG 2BP 180

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