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EMMPRIN/CD147 Protein, Human, Recombinant (Avi & His), Biotinylated

EMMPRIN/CD147 Protein, Human, Recombinant (Avi & His), Biotinylated

产品编号 TMPJ-00159
别名: Membrane glycoprotein gp42, Basigin, HT7 antigen, Bsg, Basic immunoglobulin superfamily, CD147

Basigin/CD147 is a member of the immunoglobulin superfamily with homology to both the immunoglobulin V domain and MHC class II antigen beta-chain. This protein play important roles in variety of events including spermatogenesis, embryo implantation, neural network formation. CD147 induces the production and release of matrix metalloproteinases (MMP) in the surrounding mesenchymal cells and tumor cells, and thereby promotes invasion, metastasis, growth and survival of malignant cells. Furthermore, CD147 also serves as a receptor for extracellular cyclophilinthe and its association with integrins might be important in signal transduction. CD147 displays increased expression in many cancers, and it has been previously demonstrated to participate in cancer metastasis and progression.

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EMMPRIN/CD147 Protein, Human, Recombinant (Avi & His), Biotinylated
规格 价格/CNY 货期 数量
20 μg ¥ 2,260 5日内发货
100 μg ¥ 6,130 5日内发货
夏季3重特惠
药物设计专题培训
Chloroquine限时半价
产品目录号及名称: EMMPRIN/CD147 Protein, Human, Recombinant (Avi & His), Biotinylated (TMPJ-00159)
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产品性质
产品描述 Basigin/CD147 is a member of the immunoglobulin superfamily with homology to both the immunoglobulin V domain and MHC class II antigen beta-chain. This protein play important roles in variety of events including spermatogenesis, embryo implantation, neural network formation. CD147 induces the production and release of matrix metalloproteinases (MMP) in the surrounding mesenchymal cells and tumor cells, and thereby promotes invasion, metastasis, growth and survival of malignant cells. Furthermore, CD147 also serves as a receptor for extracellular cyclophilinthe and its association with integrins might be important in signal transduction. CD147 displays increased expression in many cancers, and it has been previously demonstrated to participate in cancer metastasis and progression.
种属 Human
表达系统 HEK293 Cells
标签 C-Avi-6xHis
蛋白编号 P35613-2
别名 Membrane glycoprotein gp42, Basigin, HT7 antigen, Bsg, Basic immunoglobulin superfamily, CD147
氨基酸序列 Ala22-His205
蛋白构建 Ala22-His205
蛋白纯度 Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
分子量 30-45 KDa (reducing condition)
内毒素 < 0.1 ng/µg (1 EU/µg) as determined by LAL test.
缓冲液 Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4.
复溶方法 Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
存储

Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

运输方式

In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice.

研究背景 Basigin/CD147 is a member of the immunoglobulin superfamily with homology to both the immunoglobulin V domain and MHC class II antigen beta-chain. This protein play important roles in variety of events including spermatogenesis, embryo implantation, neural network formation. CD147 induces the production and release of matrix metalloproteinases (MMP) in the surrounding mesenchymal cells and tumor cells, and thereby promotes invasion, metastasis, growth and survival of malignant cells. Furthermore, CD147 also serves as a receptor for extracellular cyclophilinthe and its association with integrins might be important in signal transduction. CD147 displays increased expression in many cancers, and it has been previously demonstrated to participate in cancer metastasis and progression.

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Keywords

EMMPRIN/CD147 Protein, Human, Recombinant (Avi & His), Biotinylated Membrane glycoprotein gp42 CD 147 Basigin HT7 antigen Bsg Basic immunoglobulin superfamily CD-147 CD147 recombinant recombinant-proteins proteins protein

 

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