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Anti-Annexin V/ANXA5 Antibody (2Q736)

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Anti-Annexin V/ANXA5 Antibody (2Q736)
产品编号 TMAC-00215
别名 RPRGL3, PP4, HEL-S-7, ENX2, ANX5, annexin A5

Anti-Annexin V/ANXA5 Antibody (2Q736) 是一种 Rabbit 抗体,靶向 Annexin V/ANXA5。Anti-Annexin V/ANXA5 Antibody (2Q736) 可用于 WB,ICC/IF,FCM。

Anti-Annexin V/ANXA5 Antibody (2Q736)

Anti-Annexin V/ANXA5 Antibody (2Q736)

Rating icon 还可以
Anti-Annexin V/ANXA5 Antibody (2Q736)
产品编号 TMAC-00215 别名 RPRGL3, PP4, HEL-S-7, ENX2, ANX5, annexin A5

Anti-Annexin V/ANXA5 Antibody (2Q736) 是一种 Rabbit 抗体,靶向 Annexin V/ANXA5。Anti-Annexin V/ANXA5 Antibody (2Q736) 可用于 WB,ICC/IF,FCM。

规格价格库存数量
50 μL
¥ 1,490
5日内发货
100 μL
¥ 2,485
5日内发货
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产品介绍

生物活性
产品描述
Anti-Annexin V/ANXA5 Antibody (2Q736) is a Rabbit antibody targeting Annexin V/ANXA5. Anti-Annexin V/ANXA5 Antibody (2Q736) can be used in WB,ICC/IF,FCM.
别名RPRGL3, PP4, HEL-S-7, ENX2, ANX5, annexin A5
Ig Type
IgG
交叉反应
Human,Mouse,Rat
验证活性
1. Western blot analysis of Annexin V on different lysates using anti-Annexin V antibody at 1/1,000 dilution. Positive control: Lane 1: Hela, Lane 2: HepG2, Lane 3: JAR.
2. ICC staining Annexin V in Hela cells (red). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
3. ICC staining Annexin V in A431 cells (red). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
4. Flow cytometric analysis of Hela cells with Annexin V antibody at 1/50 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black). Alexa Fluor 488-conjugated goat anti rabbit IgG was used as the secondary antibody.
应用
推荐剂量
WB: 1:1000; ICC/IF: 1:100-500; FCM: 1:50-100
抗体种类
Monoclonal
宿主来源Rabbit
构建方式Recombinant Antibody
纯化方式ProA affinity purified
性状Liquid
缓冲液1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
研究背景The annexin family of calcium-binding proteins is composed of at least ten mammalian genes and is characterized by a conserved core domain, which binds phospholipids in a Ca2+-dependent manner, and a unique amino-terminal region, which may confer binding specificity. Annexin family members have been implicated as regulators of such diverse processes as ion flux, endocytosis and exocytosis, and cellular adhesion. For example, the crystal structure of Annexin III has suggested a hydrophilic amino-terminus with possible Ca2+ channel activity. Similarly, Annexin V has ion channel properties. Annexin IV, also referred to as endonexin, functions to regulate Cl-flux by mediating calmodulin kinase II (CaMKII) activity and Annexin V has been shown to regulate PKC activity. Annexin V is ubiquitously expressed at high levels in tissues and cells grown in tissue culture, while Annexin VIII exhibits a more limited distribution. Where co-expressed in the same tissues, Annexin VIII is often expressed at a 100-fold lower level than Annexin V. However, Annexin VIII is preferentially expressed in acute promyelocytic leukemia (APL) cells, which may relate to its role in hematopoietic cell differentiation.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Protein
Uniprot ID
化学信息
分子量Theoretical: 36 kDa.
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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