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Anti-Ferritin light chain Antibody (9K512)
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产品编号 TMAC-01457
别名 NBIA3, MGC71996, LFTD, ferritin, light polypeptide
Anti-Ferritin light chain Antibody (9K512) 是一种 Rabbit 抗体，靶向 Ferritin light chain。Anti-Ferritin light chain Antibody (9K512) 可用于 WB,IHC,IP,ICC。
Anti-Ferritin light chain Antibody (9K512)
Anti-Ferritin light chain Antibody (9K512)
还可以产品编号 TMAC-01457 别名 NBIA3, MGC71996, LFTD, ferritin, light polypeptide
Anti-Ferritin light chain Antibody (9K512) 是一种 Rabbit 抗体，靶向 Ferritin light chain。Anti-Ferritin light chain Antibody (9K512) 可用于 WB,IHC,IP,ICC。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,490 | 5日内发货 | |
| 100 μL | ¥ 2,485 | 5日内发货 |
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产品介绍
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偶联与修饰
抗原信息
化学信息
| 产品描述 | Anti-Ferritin light chain Antibody (9K512) is a Rabbit antibody targeting Ferritin light chain. Anti-Ferritin light chain Antibody (9K512) can be used in WB,IHC,IP,ICC. |
| 别名 | NBIA3, MGC71996, LFTD, ferritin, light polypeptide |
| Ig Type | IgG |
| 交叉反应 | Human,Mouse,Rat |
| 验证活性 | 1. Western blot analysis of Ferritin Light Chain on rat liver tissue lysate using anti-Ferritin Light Chain antibody at 1/1,000 dilution. 2. Immunohistochemical analysis of paraffin-embedded human liver tissue using anti-Ferritin Light Chain antibody. Counter stained with hematoxylin. 3. Immunohistochemical analysis of paraffin-embedded human brain tissue using anti-Ferritin Light Chain antibody. Counter stained with hematoxylin. 4. Immunohistochemical analysis of paraffin-embedded human kidney tissue using anti-Ferritin Light Chain antibody. Counter stained with hematoxylin. 5. Immunohistochemical analysis of paraffin-embedded mouse testes tissue using anti-Ferritin Light Chain antibody. Counter stained with hematoxylin. 6. Immunohistochemical analysis of paraffin-embedded mouse kidney tissue using anti-Ferritin Light Chain antibody. Counter stained with hematoxylin. |
| 应用 | |
| 推荐剂量 | WB: 1:1000-5000; IHC: 1:100-500; ICC: 1:100-200 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 构建方式 | Recombinant Antibody |
| 纯化方式 | ProA affinity purified |
| 性状 | Liquid |
| 缓冲液 | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| 研究背景 | Mammalian ferritins consist of 24 subunits made up of two types of polypeptide chains, ferritin heavy chain and ferritin light chain, which each have unique functions. Ferritin heavy chains catalyze the first step in iron storage, the oxidation of Fe (II), whereas ferritin light chains promote the nucleation of ferrihydrite, enabling storage of Fe (III). The most prominent role of mammalian ferritins is to provide iron-buffering capacity to cells. In addition to iron buffering, heavy chain ferritin is also involved in the regulation of thymidine biosynthesis via increased expression of cytoplasmic serine hydroxymethyltransferase, which is a limiting factor in thymidylate synthesis in MCF-7 cells. Light chain ferritin is involved in cataracts by at least two mechanisms, hereditary hyperferritinemia cataract syndrome, in which light chain ferritin is overexpressed, and oxidative stress, an important factor in the development of ageing-related cataracts. The gene encoding human ferritin heavy chain maps to chromosome 11q13 and the human ferritin light chain gene maps to chromosome 19q13.3-q13.4. |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Protein |
| Uniprot ID |
| 分子量 | Theoretical: 54 kDa. |
存储&运输
| 储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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