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Anti-Phospho-STAT5A (Y694) Antibody (5T706) 是一种 Rabbit 抗体,靶向 Phospho-STAT5A (Y694)。Anti-Phospho-STAT5A (Y694) Antibody (5T706) 可用于 WB,IHC。
Anti-Phospho-STAT5A (Y694) Antibody (5T706) 是一种 Rabbit 抗体,靶向 Phospho-STAT5A (Y694)。Anti-Phospho-STAT5A (Y694) Antibody (5T706) 可用于 WB,IHC。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
50 μL | ¥ 1,480 | 5日内发货 | |
100 μL | ¥ 2,495 | 5日内发货 |
产品描述 | Anti-Phospho-STAT5A (Tyr694) Antibody (5T706) 是一种 Rabbit 抗体,靶向 Phospho-STAT5A (Tyr694)。Anti-Phospho-STAT5A (Tyr694) Antibody (5T706) 可用于 WB,IHC。 |
别名 | Transcription factor STAT5B, Transcription factor STAT5A, STAT5B, STAT5A (p-Y694), STAT5A (p-Tyr394), STAT5, STAT 5B, STAT 5A, STA5A_HUMAN, Signal Transducer and Activator of Transcription 5B, Signal transducer and activator of transcription 5A, p-STAT5A (Y694), p-STAT5A (Tyr394), Phospho-STAT5A (Y694), MGF |
Ig Type | IgG |
交叉反应 | Human,Mouse |
验证活性 | 1. Western blot analysis of Phospho-Stat5 (Y694) on mouse liver lysates using anti-Phospho-Stat5 (Y694) antibody at 1/1,000 dilution. |
应用 | |
推荐剂量 | WB: 1:1000-2000; IHC: 1:50-200 |
抗体种类 | Monoclonal |
宿主来源 | Rabbit |
构建方式 | Hybridoma Monoclonal Antibody |
纯化方式 | ProA affinity purified |
性状 | Liquid |
缓冲液 | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
研究背景 | Stat5 (Signal Transducers and Activators of Transcription 5) is important in regulating T cell functions involving the receptors for Interleukin-2 (IL-2). IL-2 stimulates the rapid phosphorylation of both serine and tyrosine residues of Stat5a and Stat5b in human T lymphocytes and in several IL-2-responsive lymphocytic cell lines. IL-2 differentially induces serine phosphorylation of Stat5a and Stat5b on Ser726 and Ser731, respectively. Stat5b is preferentially phosphorylated and displays more protracted serine phosphorylation kinetics than Stat5a. Both the acid-rich region and the COOH terminus of IL-2Rb can independently mediate IL-2-induced Stat 5a/b serine phosphorylation, suggesting that Stat5a/b serine phosphorylation occurs at a postreceptor level. Stat5a is phosphorylated on Tyr694 in a prolactin-sensitive manner, whereas serine phosphorylation is constitutive. Activation of Stat5 by IL-2 may help govern the biological effects of IL-2 during the immune response. |
偶联 | Unconjugated |
其他可选修饰符 | Phospho |
免疫原 | A synthesized phosphopeptide: human Stat5 around the phosphorylation site of Tyr694 |
抗原种属 | human |
Uniprot ID |
分子量 | Theoretical: 90 kDa. |
储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
运输方式 | Shipping with blue ice. |
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