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Anti-SERCA2 Antibody (4Y401)

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货号 TMAB-12668

Anti-SERCA2 Antibody (4Y401) 是一种 Rabbit 抗体，靶向 SERCA2。Anti-SERCA2 Antibody (4Y401) 可用于 WB,IHC-P,IHC-Fr,ICC/IF,IF。

Anti-SERCA2 Antibody (4Y401)

Anti-SERCA2 Antibody (4Y401)

一键复制产品信息
Rating icon 还可以
货号 TMAB-12668

Anti-SERCA2 Antibody (4Y401) 是一种 Rabbit 抗体，靶向 SERCA2。Anti-SERCA2 Antibody (4Y401) 可用于 WB,IHC-P,IHC-Fr,ICC/IF,IF。

规格价格库存数量
25 μL
¥ 795
5日内发货
50 μL
¥ 1,395
5日内发货
100 μL
¥ 2,490
5日内发货
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产品介绍

生物活性
产品描述
Anti-SERCA2 Antibody (4Y401) is a Rabbit antibody targeting SERCA2. Anti-SERCA2 Antibody (4Y401) can be used in WB,IHC-P,IHC-Fr,ICC/IF,IF.
Ig Type
IgG
克隆号
4Y401
反应种属
Human,Mouse,Rat
应用WBIHC-PIHC-FrICC/IFIF
推荐剂量
WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; ICC/IF: 1:50-200; IF: 1:100-500
抗体种类
Monoclonal
宿主来源Rabbit
亚细胞定位Endoplasmic reticulum membrane; Multi-pass membrane protein. Sarcoplasmic reticulum membrane; Multi-pass membrane protein.
组织特异性Isoform 1 is widely expressed in smooth muscle and nonmuscle tissues such as in adult skin epidermis, with highest expression in liver, pancreas and lung, and intermediate expression in brain, kidney and placenta. Also expressed at lower levels in heart and skeletal muscle. Isoforms 2 and 3 are highly expressed in the heart and slow twitch skeletal muscle. Expression of isoform 3 is predominantly restricted to cardiomyocytes and in close proximity to the sarcolemma. Both isoforms are mildly expressed in lung, kidney, liver, pancreas and placenta. Expression of isoform 3 is amplified during monocytic differentiation and also observed in the fetal heart.
构建方式Recombinant Antibody
纯化方式Protein A purified
性状Liquid
缓冲液10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
研究背景This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol to the sarcoplasmic reticulum lumen. Involved in autophagy in response to starvation. Upon interaction with VMP1 and activation, controls ER-isolation membrane contacts for autophagosome formation.
抗原信息
免疫原
A synthesized peptide: human SERCA2
抗原种属
Human
基因名称
ATP2A2
基因ID
488
蛋白名称
Sarcoplasmic/endoplasmic reticulum calcium ATPase 2
Uniprot ID
P16615
功能
This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol to the sarcoplasmic reticulum lumen. Isoform 2 is involved in the regulation of the contraction/relaxation cycle.
化学信息
分子量Theoretical: 115 kDa. Actual: 110, 140 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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