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Anti-APOBEC3B Polyclonal Antibody

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货号 TMAB-02759

Anti-APOBEC3B Polyclonal Antibody 是一种 Rabbit 抗体，靶向 APOBEC3B。Anti-APOBEC3B Polyclonal Antibody 可用于 WB,IHC-P,IHC-Fr,IF。

Anti-APOBEC3B Polyclonal Antibody

Anti-APOBEC3B Polyclonal Antibody

一键复制产品信息
Rating icon 还可以
货号 TMAB-02759

Anti-APOBEC3B Polyclonal Antibody 是一种 Rabbit 抗体，靶向 APOBEC3B。Anti-APOBEC3B Polyclonal Antibody 可用于 WB,IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,170
5日内发货
100 μL
¥ 1,965
5日内发货
200 μL
¥ 2,790
5日内发货
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产品介绍

生物活性
产品描述
Anti-APOBEC3B Polyclonal Antibody is a Rabbit antibody targeting APOBEC3B. Anti-APOBEC3B Polyclonal Antibody can be used in WB,IHC-P,IHC-Fr,IF.
Ig Type
IgG
反应种属
Human,Rat,Mouse
应用WBIHC-PIHC-FrIF
推荐剂量
WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Nucleus.
组织特异性Expressed at high and moderate levels in peripheral blood leukocytes, spleen, testes, heart, thymus, prostate and ovary. Also expressed at low levels in several other tissues.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景APOBEC proteins inhibit retroviruses by deaminating cytosine residues of viral RNA and DNA. The seven APOBEC3 genes or pseudogenes are found in a cluster thought to result from gene duplication on chromosome 22. APOBEC3 proteins are thought to be RNA editing enzymes and have roles in cell growth. APOBEC3B, also known as phorbolin-1-related protein or phorbolin-2/3, is a 382 amino acid protein belonging to the cytidine and deoxycytidylate deaminase family. APOBEC3B lacks cytidine deaminase activity on RNA molecules, but has been shown to bind to apoB and AU-rich RNAs. APOBEC3B forms a homodimer and interacts with APOBEC3G. APOBEC3B is expressed at at moderate levels in heart, testis, thymus, prostate, ovary, spleen and peripheral blood leukocytes.
抗原信息
免疫原
KLH conjugated synthetic peptide: human APOBEC3B
抗原种属
Human
基因名称
APOBEC3B
基因ID
9582
蛋白名称
DNA dC->dU-editing enzyme APOBEC-3B
Uniprot ID
Q9UH17
功能
APOBEC3B is a member of the cytidine deaminase gene family. However, it lacks cytidine deaminase activity, at least on RNA molecules (monomeric nucleoside substrates or synthetic apoB, NF1 and NAT1 RNA template). It binds to apoB and AU-rich RNAs. It is unable to reduce HIV-1 infectivity in vitro.
化学信息
分子量Theoretical: 46 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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