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Anti-Phospho-p38 MAPK (Thr180, Tyr182) Polyclonal Antibody

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Anti-Phospho-p38 MAPK (Thr180, Tyr182) Polyclonal Antibody
产品编号 TMAB-01472

Anti-Phospho-p38 MAPK (Thr180, Tyr182) Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Phospho-p38 MAPK (Thr180, Tyr182)。Anti-Phospho-p38 MAPK (Thr180, Tyr182) Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

Anti-Phospho-p38 MAPK (Thr180, Tyr182) Polyclonal Antibody

Anti-Phospho-p38 MAPK (Thr180, Tyr182) Polyclonal Antibody

Rating icon 还可以
Anti-Phospho-p38 MAPK (Thr180, Tyr182) Polyclonal Antibody
产品编号 TMAB-01472

Anti-Phospho-p38 MAPK (Thr180, Tyr182) Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Phospho-p38 MAPK (Thr180, Tyr182)。Anti-Phospho-p38 MAPK (Thr180, Tyr182) Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,165
5日内发货
100 μL
¥ 1,970
5日内发货
200 μL
¥ 2,795
5日内发货
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产品介绍

生物活性
产品描述
Anti-Phospho-p38 MAPK (Thr180, Tyr182) Polyclonal Antibody is a Rabbit antibody targeting Phospho-p38 MAPK (Thr180, Tyr182). Anti-Phospho-p38 MAPK (Thr180, Tyr182) Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
交叉反应
Human,Mouse,Rat (predicted:Dog,Rabbit)
验证活性
1. Paraformaldehyde-fixed, paraffin embedded Mouse colon; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Antibody incubation with Phospho-P38 MAPK (Thr180 + Tyr182) Polyclonal Antibody, Unconjugated (TMAB-01472) at 1:200 overnight at 4°C, followed by conjugation to the secondary antibody and DAB staining.
2. Paraformaldehyde-fixed, paraffin embedded Mouse brain; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Antibody incubation with Phospho-P38 MAPK (Thr180 + Tyr182) Polyclonal Antibody, Unconjugated (TMAB-01472) at 1:200 overnight at 4°C, followed by conjugation to the secondary antibody and DAB staining.
3. Paraformaldehyde-fixed, paraffin embedded Rat colon; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Antibody incubation with Phospho-P38 MAPK (Thr180 + Tyr182) Polyclonal Antibody, Unconjugated (TMAB-01472) at 1:200 overnight at 4°C, followed by conjugation to the secondary antibody and DAB staining.
4. Paraformaldehyde-fixed, paraffin embedded Rat brain; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Antibody incubation with Phospho-P38 MAPK (Thr180 + Tyr182) Polyclonal Antibody, Unconjugated (TMAB-01472) at 1:200 overnight at 4°C, followed by conjugation to the secondary antibody and DAB staining.
5. Paraformaldehyde-fixed, paraffin embedded Rat kidney; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Antibody incubation with Phospho-P38 MAPK (Thr180 + Tyr182) Polyclonal Antibody, Unconjugated (TMAB-01472) at 1:200 overnight at 4°C, followed by conjugation to the secondary antibody and DAB staining.
6. Paraformaldehyde-fixed, paraffin embedded Human colon cancer; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Antibody incubation with Phospho-P38 MAPK (Thr180 + Tyr182) Polyclonal Antibody, Unconjugated (TMAB-01472) at 1:200 overnight at 4°C, followed by conjugation to the secondary antibody and DAB staining.
7. Paraformaldehyde-fixed, paraffin embedded Human colon; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Antibody incubation with Phospho-P38 MAPK (Thr180 + Tyr182) Polyclonal Antibody, Unconjugated (TMAB-01472) at 1:200 overnight at 4°C, followed by conjugation to the secondary antibody and DAB staining.
8. Paraformaldehyde-fixed, paraffin embedded Human Brain; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Antibody incubation with Phospho-P38 MAPK (Thr180 + Tyr182) Polyclonal Antibody, Unconjugated (TMAB-01472) at 1:200 overnight at 4°C, followed by conjugation to the secondary antibody and DAB staining.
应用
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Cytoplasm. Nucleus.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
研究背景The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various environmental stresses and proinflammatory cytokines. The activation requires its phosphorylation by MAP kinase kinases(MKKs), or its autophosphorylation triggered by the interaction of MAP3K7IP1/TAB1 protein with this kinase. The substrates of this kinase include transcription regulator ATF2, MEF2C, and MAX, cell cycle regulator CDC25B, and tumor suppressor p53, which suggest the roles of this kinase in stress related transcription and cell cycle regulation, as well as in genotoxic stress response. Four alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.
抗原信息
免疫原
KLH conjugated Synthesised phosphopeptide: human p38 MAPK around the phosphorylation site of Thr180/Tyr182
抗原种属
Human
基因ID
Uniprot ID
研究领域
MAPK pathway,TLR Signaling,Other Cell Signaling Kits,MAPK Pathway
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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