Anti-PTH Antibody (4H10)

Name: Anti-PTH Antibody (4H10)
Brand: TargetMol
SKU: TMAY-02528
Rating: 4.5 (1 reviews)

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产品编号 TMAY-02528

Anti-PTH Antibody (4H10) 是一种 Mouse 抗体，靶向 PTH。Anti-PTH Antibody (4H10) 可用于 ELISA(Cap)。

Anti-PTH Antibody (4H10)

还可以

产品编号 TMAY-02528

Anti-PTH Antibody (4H10) 是一种 Mouse 抗体，靶向 PTH。Anti-PTH Antibody (4H10) 可用于 ELISA(Cap)。

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生物活性

产品描述	Anti-PTH Antibody (4H10) is a Mouse antibody targeting PTH. Anti-PTH Antibody (4H10) can be used in ELISA(Cap).
Ig Type	Monoclonal Mouse IgG1
克隆号	4H10
交叉反应	Human
应用	ELISA(Cap)
抗体种类	Monoclonal
宿主来源	Mouse
构建方式	This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human PTH / PTH1 / Parathyroid Hormone (rh PTH / PTH1 / Parathyroid Hormone; TMPY-02764; P01270; Ser32-Phe65). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.
纯化方式	Protein A
性状	Liquid
缓冲液	0.2 μm filtered solution in PBS
研究背景	Parathyroid hormone (PTH), parathormone or parathyrin, is secreted by the chief cells of the parathyroid glands as a polypeptide. PTH elevates calcium level by dissolving the salts in bone and preventing their renal excretion. Parathyroid hormone (PTH) has been proved to play a pivotal role in maintaining myocardial contractility as well as effective natriuresis, and possible pathogenic mechanisms contributing to heart failure secondary to hypocalcemia and hypoparathyroidism. With the increased population of preosteoblastic lineages and the osteoblastic activation, Parathyroid hormone (PTH) drives anabolism in bone. Experiments have recently reported that PTH affects bone cells in a dual pathway - mediating osteoblastic (preosteoblastic) activities or osteocytic synthesis of sclerostin. Defects in PTH are a cause of familial isolated hypoparathyroidism (FIH), also called autosomal dominant hypoparathyroidism or autosomal dominant hypocalcemia. FIH is characterized by hypocalcemia and hyperphosphatemia due to inadequate secretion of parathyroid hormone. Symptoms are seizures, tetany and cramps.

偶联与修饰

偶联	Unconjugated

抗原信息

免疫原	Recombinant Human PTH / PTH1 / Parathyroid Hormone Protein (TMPY-02764)
抗原种属	Human

存储&运输

储存方式	Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
运输方式	Shipping with blue ice.