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Anti-NR3C2/Mineralocorticoid receptor Polyclonal Antibody 2

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货号 TMAB-09621

Anti-NR3C2/Mineralocorticoid receptor Polyclonal Antibody 2 是一种 Rabbit 抗体，靶向 NR3C2/Mineralocorticoid receptor。Anti-NR3C2/Mineralocorticoid receptor Polyclonal Antibody 2 可用于 IHC-P,IHC-Fr,IF,FCM。

Anti-NR3C2/Mineralocorticoid receptor Polyclonal Antibody 2

Anti-NR3C2/Mineralocorticoid receptor Polyclonal Antibody 2

一键复制产品信息
Rating icon 还可以
货号 TMAB-09621

Anti-NR3C2/Mineralocorticoid receptor Polyclonal Antibody 2 是一种 Rabbit 抗体，靶向 NR3C2/Mineralocorticoid receptor。Anti-NR3C2/Mineralocorticoid receptor Polyclonal Antibody 2 可用于 IHC-P,IHC-Fr,IF,FCM。

规格价格库存数量
50 μL
¥ 1,160
5日内发货
100 μL
¥ 1,970
5日内发货
200 μL
¥ 2,795
5日内发货
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产品介绍

生物活性
产品描述
Anti-NR3C2/Mineralocorticoid receptor Polyclonal Antibody 2 is a Rabbit antibody targeting NR3C2/Mineralocorticoid receptor. Anti-NR3C2/Mineralocorticoid receptor Polyclonal Antibody 2 can be used in IHC-P,IHC-Fr,IF,FCM.
Ig Type
IgG
反应种属
Human,Mouse (predicted:Rat,Chicken,Dog,Pig,Cow,Rabbit)
应用IHC-PIHC-FrIFFCM
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500; FCM: 1μg/Test
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Cytoplasm. Nucleus. Endoplasmic reticulum membrane; Peripheral membrane protein. Note=Cytoplasmic and nuclear in the absence of ligand; nuclear after ligand-binding. When bound to HSD11B2, it is found associated with the endoplasmic reticulum membrane.
组织特异性Ubiquitous. Highly expressed in distal tubules, convoluted tubules and cortical collecting duct in kidney, and in sweat glands. Detected at lower levels in cardiomyocytes, in epidermis and in colon enterocytes.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景Steroid receptors are ligand dependent, intracellular proteins that stimulate transcription of specific genes by binding to specific DNA sequences following activation by the appropriate hormone. Mineralocorticoids are a family of steroids, secreted by the adrenal cortex, necessary for the regulation of a number of metabolic processes including electrolyte regulation. These compounds exert their effect through their interaction with the mineralocorticoid receptor and that complex's subsequent association with DNA. Given the function of mineralocorticoids, it is not surprising to find that the kidney is a primary target organ for mineralocorticoids and that this organ has been shown to contain Mineralocorticoid Receptor.
抗原信息
免疫原
KLH conjugated synthetic peptide: human Mineralocorticoid receptor
抗原种属
Human
基因名称
NR3C2
基因ID
4306
蛋白名称
Mineralocorticoid receptor
Uniprot ID
P08235
功能
Receptor for both mineralocorticoids (MC) such as aldosterone and glucocorticoids (GC) such as corticosterone or cortisol. Binds to mineralocorticoid response elements (MRE) and transactivates target genes. The effect of MC is to increase ion and water transport and thus raise extracellular fluid volume and blood pressure and lower potassium levels.
化学信息
分子量Theoretical: 107 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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