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Anti-TGF beta 1 Antibody (6A904)

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货号 TMAB-13491

Anti-TGF beta 1 Antibody (6A904) 是一种 Rabbit 抗体,靶向 TGF beta 1。Anti-TGF beta 1 Antibody (6A904) 可用于 WB。

Anti-TGF beta 1 Antibody (6A904)

Anti-TGF beta 1 Antibody (6A904)

一键复制产品信息
Rating icon 还可以
货号 TMAB-13491

Anti-TGF beta 1 Antibody (6A904) 是一种 Rabbit 抗体,靶向 TGF beta 1。Anti-TGF beta 1 Antibody (6A904) 可用于 WB。

规格价格库存数量
25 μL
¥ 790
5日内发货
50 μL
¥ 1,385
5日内发货
100 μL
¥ 2,480
5日内发货
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产品介绍


生物活性
产品描述
Anti-TGF beta 1 Antibody (6A904) is a Rabbit antibody targeting TGF beta 1. Anti-TGF beta 1 Antibody (6A904) can be used in WB.
Ig Type
IgG
克隆号
6A904
反应种属
Human
应用WB
推荐剂量
WB: 1:500-2000
抗体种类
Monoclonal
宿主来源Rabbit
亚细胞定位Secreted, extracellular space, extracellular matrix.
组织特异性Highly expressed in bone. Abundantly expressed in articular cartilage and chondrocytes and is increased in osteoarthritis (OA). Co-localizes with ASPN in chondrocytes within OA lesions of articular cartilage.
构建方式Recombinant Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
研究背景This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate a latency-associated peptide (LAP) and a mature peptide, and is found in either a latent form composed of a mature peptide homodimer, a LAP homodimer, and a latent TGF-beta binding protein, or in an active form consisting solely of the mature peptide homodimer. The mature peptide may also form heterodimers with other TGFB family members. This encoded protein regulates cell proliferation, differentiation and growth, and can modulate expression and activation of other growth factors including interferon gamma and tumor necrosis factor alpha. This gene is frequently upregulated in tumor cells, and mutations in this gene result in Camurati-Engelmann disease. [provided by RefSeq, Aug 2016]
抗原信息
免疫原
A synthesized peptide: human TGF beta 1
抗原种属
Human
基因名称
TGFB1
基因ID
蛋白名称
Transforming growth factor beta-1 proprotein
Uniprot ID
功能
Multifunctional protein that controls proliferation, differentiation and other functions in many cell types. Many cells synthesize TGFB1 and have specific receptors for it. It positively and negatively regulates many other growth factors. It plays an important role in bone remodeling as it is a potent stimulator of osteoblastic bone formation, causing chemotaxis, proliferation and differentiation in committed osteoblasts.
化学信息
分子量Theoretical: 44 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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