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Anti-Phospho-IGF1R/CD221 (Tyr1280) Polyclonal Antibody

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Anti-Phospho-IGF1R/CD221 (Tyr1280) Polyclonal Antibody
产品编号 TMAC-02096
别名 p-IGF1R/CD221 (Y1280), p-IGF1R/CD221 (Tyr1280), IGF1R/CD221 (p-Y1280), IGF1R/CD221 (p-Tyr1280)

Anti-Phospho-IGF1R/CD221 (Tyr1280) Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Phospho-IGF1R/CD221 (Tyr1280)。Anti-Phospho-IGF1R/CD221 (Tyr1280) Polyclonal Antibody 可用于 WB。

Anti-Phospho-IGF1R/CD221 (Tyr1280) Polyclonal Antibody

Anti-Phospho-IGF1R/CD221 (Tyr1280) Polyclonal Antibody

Rating icon 还可以
Anti-Phospho-IGF1R/CD221 (Tyr1280) Polyclonal Antibody
产品编号 TMAC-02096 别名 p-IGF1R/CD221 (Y1280), p-IGF1R/CD221 (Tyr1280), IGF1R/CD221 (p-Y1280), IGF1R/CD221 (p-Tyr1280)

Anti-Phospho-IGF1R/CD221 (Tyr1280) Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Phospho-IGF1R/CD221 (Tyr1280)。Anti-Phospho-IGF1R/CD221 (Tyr1280) Polyclonal Antibody 可用于 WB。

规格价格库存数量
50 μL
¥ 1,480
5日内发货
100 μL
¥ 2,245
5日内发货
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产品介绍

生物活性
产品描述
Anti-Phospho-IGF1R/CD221 (Tyr1280) Polyclonal Antibody is a Rabbit antibody targeting Phospho-IGF1R/CD221 (Tyr1280). Anti-Phospho-IGF1R/CD221 (Tyr1280) Polyclonal Antibody can be used in WB.
别名p-IGF1R/CD221 (Y1280), p-IGF1R/CD221 (Tyr1280), IGF1R/CD221 (p-Y1280), IGF1R/CD221 (p-Tyr1280)
Ig Type
IgG
交叉反应
Human
验证活性
1. Western blot analysis of extract from 293 cells using IGF-1R (Phospho-Tyr1280) Antibody TMAC-02096.
应用
WB
抗体种类
Polyclonal
宿主来源Rabbit
构建方式Polyclonal Antibody
纯化方式Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.
性状Liquid
缓冲液Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
研究背景This receptor binds insulin-like growth factor 1 (IGF1) with a high affinity and IGF2 with a lower affinity. It has a tyrosine-protein kinase activity, which is necessary for the activation of the IGF1-stimulated downstream signaling cascade. When present in a hybrid receptor with INSR, binds IGF1. Ref.19 shows that hybrid receptors composed of IGF1R and INSR isoform Long are activated with a high affinity by IGF1, with low affinity by IGF2 and not significantly activated by insulin, and that hybrid receptors composed of IGF1R and INSR isoform Short are activated by IGF1, IGF2 and insulin. In contrast, Ref.21 shows that hybrid receptors composed of IGF1R and INSR isoform Long and hybrid receptors composed of IGF1R and INSR isoform Short have similar binding characteristics, both bind IGF1 and have a low affinity for insulin.
偶联与修饰
偶联
Unconjugated
其他可选修饰符
Phospho
抗原信息
免疫原
Peptide sequence around phosphorylation site of tyrosine 1280 (S-F-Y(p)-Y-S) derived from Human IGF-1R
抗原种属
human
Uniprot ID
P08069
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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关键词

pIGF1R/CD221 (Y1280)pIGF1R/CD221 (Tyr1280)IGF1R/CD221 (pY1280)IGF1R/CD221 (pTyr1280)IGF1R/CD221 (phospho-Y1280)IGF1R/CD221 (phospho-Tyr1280)

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