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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-SIPA1L1 Polyclonal Antibody

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货号 TMAB-12806

Anti-SIPA1L1 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 SIPA1L1。Anti-SIPA1L1 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

Anti-SIPA1L1 Polyclonal Antibody

Anti-SIPA1L1 Polyclonal Antibody

一键复制产品信息
Rating icon 还可以
货号 TMAB-12806

Anti-SIPA1L1 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 SIPA1L1。Anti-SIPA1L1 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,175
5日内发货
100 μL
¥ 1,960
5日内发货
200 μL
¥ 2,795
5日内发货
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产品介绍

生物活性
产品描述
Anti-SIPA1L1 Polyclonal Antibody is a Rabbit antibody targeting SIPA1L1. Anti-SIPA1L1 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
反应种属
Mouse,Rat (predicted:Human,Chicken,Dog,Pig,Cow,Horse,Sheep)
应用IHC-PIHC-FrIF
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Intracellular
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景SIPA1L1 (Signal-induced proliferation associated-like protein 1) is a member of the SIPA1 family of RapGAPs. SIPA1L1 was initially identified as a binding partner and degradation target of the E6 oncoprotein of high-risk papillomaviruses. Recently, it was discovered that Casein kinase I epsilon (CKIe), a Wnt-regulated kinase that regulates Wnt/b-catenin signaling, also can bind to the carboxy-terminus of SIPA1L1. CKIe phosphorylates SIPA1L1, thereby reducing its stability and alleviating its inhibition of Rap1, a protein required for Wnt8/CKIe-mediated gastrulation during embryogenesis, suggesting SIPA1L1 plays important roles in embryo development as well as control of cell proliferation.
抗原信息
免疫原
KLH conjugated synthetic peptide: human SIPA1L1
抗原种属
Human
基因名称
SIPA1L1
基因ID
26037
蛋白名称
Signal-induced proliferation-associated 1-like protein 1
Uniprot ID
O43166
化学信息
分子量Theoretical: 200 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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