VPAC2 重组蛋白, Human (mFc)

VPAC2 Protein, Human, Recombinant (mFc)

产品编号 TMPY-01120

VIP and PACAP receptor 2, or VIPR2 encodes the VPAC2 receptor, which binds both VIP and PACAP. VPAC2 is expressed throughout the central nervous system and the periphery. Mutations in the VIPR2 homolog in the mouse cause hypoactivity, as well as disruptions in circadian rhythm. Duplications of the neuropeptide receptor gene VIPR2 confer significant risk for schizophrenia.

VPAC2 Protein, Human, Recombinant (mFc)

产品编号 TMPY-01120

规格	价格	库存	数量
100 μg	¥ 4,460	5日内发货

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常见问题解答

问动物不能耐受 DMSO，给药时 DMSO量应该如何控制？

答对于普通的老鼠，DMSO 的浓度应控制在 10% 以下，对于裸鼠、转基因小鼠、耐受性弱的老鼠等，DMSO 浓度需控制在2%以下。对于首次操作的抑制剂，建议先做溶剂阴性对照，确认溶解对动物无非特异性影响。

问小规格产品，收到瓶子后看不到任何东西？

答由于产品规格小，粉末在运输过程中产生的静电导致过于分散，管壁和盖子上皆会粘着，您可以放心，离心后加入适量溶剂直接配制母液、充分溶解即可。

问超声应使用什么仪器？

答建议使用“超声清洗仪”，不推荐用“超声破碎仪”。

问超声应使用什么样的频率？

答频率建议使用常规的超声清洗频率即可，一般在20 kHz - 100 kHz。

问如何选择合适的溶剂？

答常用的溶剂包括DMSO、水、乙醇等。建议您根据抑制剂给出的溶解度参考，选择合适的溶剂。如果该抑制剂可以溶于DMSO，建议使用没有吸潮新开封的 DMSO，如果有潮气污染，很容易带来抑制剂降解或难溶的问题。如果该抑制剂可以溶于水，建议您根据实验类型选择无菌水、生理盐水、无菌 PBS 、培养基等作为溶剂。

产品信息

生物活性	Activity testing is in progress. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
产品描述	VIP and PACAP receptor 2, or VIPR2 encodes the VPAC2 receptor, which binds both VIP and PACAP. VPAC2 is expressed throughout the central nervous system and the periphery. Mutations in the VIPR2 homolog in the mouse cause hypoactivity, as well as disruptions in circadian rhythm. Duplications of the neuropeptide receptor gene VIPR2 confer significant risk for schizophrenia.
种属	Human
表达系统	HEK293 Cells
标签	C-mFc
蛋白编号	P41587-1
别名	VPCAP2R,VPAC2R,VPAC2,VIP-R-2,vasoactive intestinal peptide receptor 2,PACAP-R-3,PACAP-R3,DUP7q36.3,C16DUPq36.3
蛋白构建	A DNA sequence encoding the human VIPR2 (NP_003373.2) (Met1-Val126) was expressed with the Fc region of mouse IgG1 at the C-terminus. Predicted N terminal: Glu 24
蛋白纯度	> 90 % as determined by SDS-PAGE
分子量	38.1 kDa (predicted); 50.6 kDa (reducing conditions)
内毒素	< 1.0 EU/μg of the protein as determined by the LAL method.
缓冲液	Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization.
复溶方法	A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information.
存储	It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
运输方式	In general, Lyophilized powders are shipping with blue ice.
研究背景	VIP and PACAP receptor 2, or VIPR2 encodes the VPAC2 receptor, which binds both VIP and PACAP. VPAC2 is expressed throughout the central nervous system and the periphery. Mutations in the VIPR2 homolog in the mouse cause hypoactivity, as well as disruptions in circadian rhythm. Duplications of the neuropeptide receptor gene VIPR2 confer significant risk for schizophrenia.

VPAC2 Protein, Human, Recombinant (mFc)

VPAC2 Protein, Human, Recombinant (mFc)

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