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Anti-GRM7 Antibody (6J762)

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Anti-GRM7 Antibody (6J762)
产品编号 TMAC-01722
别名 OTTHUMP00000214675, OTTHUMP00000214674, OTTHUMP00000206961, mGluR7, MGLU7, Metabotropic glutamate receptor 7, GRM7_HUMAN, GRM 7, GPRC1G, Glutamate receptor metabotropic 7, GLUR7, FLJ40498

Anti-GRM7 Antibody (6J762) 是一种 Mouse 抗体,靶向 GRM7。Anti-GRM7 Antibody (6J762) 可用于 WB,ICC,FCM。

Anti-GRM7 Antibody (6J762)

Anti-GRM7 Antibody (6J762)

Rating icon 还可以
Anti-GRM7 Antibody (6J762)
产品编号 TMAC-01722 别名 OTTHUMP00000214675, OTTHUMP00000214674, OTTHUMP00000206961, mGluR7, MGLU7, Metabotropic glutamate receptor 7, GRM7_HUMAN, GRM 7, GPRC1G, Glutamate receptor metabotropic 7, GLUR7, FLJ40498

Anti-GRM7 Antibody (6J762) 是一种 Mouse 抗体,靶向 GRM7。Anti-GRM7 Antibody (6J762) 可用于 WB,ICC,FCM。

规格价格库存数量
50 μL
¥ 1,995
5日内发货
100 μL
¥ 2,995
5日内发货
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产品介绍

生物活性
产品描述
Anti-GRM7 Antibody (6J762) is a Mouse antibody targeting GRM7. Anti-GRM7 Antibody (6J762) can be used in WB,ICC,FCM.
别名OTTHUMP00000214675, OTTHUMP00000214674, OTTHUMP00000206961, mGluR7, MGLU7, Metabotropic glutamate receptor 7, GRM7_HUMAN, GRM 7, GPRC1G, Glutamate receptor metabotropic 7, GLUR7, FLJ40498
克隆号
6J762
交叉反应
Human
验证活性
1. Western blot analysis of GRM7 on human GRM7 recombinant protein using anti-GRM7 antibody at 1/1,000 dilution.
2. Western blot analysis of GRM7 on HEK293 (1) and GRM7-hIgGFc transfected HEK293 (2) cell lysate using anti-GRM7 antibody at 1/1,000 dilution.
3. ICC staining GRM7 (green) and Actin filaments (red) in Hela cells. The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
4. ICC staining GRM7 (green) and Actin filaments (red) in SMMC-7721 cells. The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
5. Flow cytometric analysis of SH-SY5Y cells with GRM7 antibody at 1/100 dilution (green) compared with an unlabelled control (cells without incubation with primary antibody; red).
应用
推荐剂量
WB: 1:500-2000; ICC: 1:50-200; FCM: 1:50-100
抗体种类
Monoclonal
宿主来源Mouse
构建方式Hybridoma Monoclonal Antibody
纯化方式ProA affinity purified
性状Liquid
缓冲液1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
研究背景L-glutamate is the major excitatory neurotransmitter in the central nervous system, and it activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors that have been divided into three groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5, and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3, while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities. Multiple transcript variants encoding different isoforms have been found for this gene.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Protein
Uniprot ID
化学信息
分子量Theoretical: 102 kDa.
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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