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Anti-GRM7 Antibody (6J762) 是一种 Mouse 抗体,靶向 GRM7。Anti-GRM7 Antibody (6J762) 可用于 WB,ICC,FCM。
Anti-GRM7 Antibody (6J762) 是一种 Mouse 抗体,靶向 GRM7。Anti-GRM7 Antibody (6J762) 可用于 WB,ICC,FCM。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
50 μL | ¥ 1,995 | 5日内发货 | |
100 μL | ¥ 2,995 | 5日内发货 |
产品描述 | Anti-GRM7 Antibody (6J762) is a Mouse antibody targeting GRM7. Anti-GRM7 Antibody (6J762) can be used in WB,ICC,FCM. |
别名 | OTTHUMP00000214675, OTTHUMP00000214674, OTTHUMP00000206961, mGluR7, MGLU7, Metabotropic glutamate receptor 7, GRM7_HUMAN, GRM 7, GPRC1G, Glutamate receptor metabotropic 7, GLUR7, FLJ40498 |
克隆号 | 6J762 |
交叉反应 | Human |
验证活性 | 1. Western blot analysis of GRM7 on human GRM7 recombinant protein using anti-GRM7 antibody at 1/1,000 dilution. 2. Western blot analysis of GRM7 on HEK293 (1) and GRM7-hIgGFc transfected HEK293 (2) cell lysate using anti-GRM7 antibody at 1/1,000 dilution. 3. ICC staining GRM7 (green) and Actin filaments (red) in Hela cells. The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. 4. ICC staining GRM7 (green) and Actin filaments (red) in SMMC-7721 cells. The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. 5. Flow cytometric analysis of SH-SY5Y cells with GRM7 antibody at 1/100 dilution (green) compared with an unlabelled control (cells without incubation with primary antibody; red). |
应用 | |
推荐剂量 | WB: 1:500-2000; ICC: 1:50-200; FCM: 1:50-100 |
抗体种类 | Monoclonal |
宿主来源 | Mouse |
构建方式 | Hybridoma Monoclonal Antibody |
纯化方式 | ProA affinity purified |
性状 | Liquid |
缓冲液 | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
研究背景 | L-glutamate is the major excitatory neurotransmitter in the central nervous system, and it activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors that have been divided into three groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5, and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3, while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities. Multiple transcript variants encoding different isoforms have been found for this gene. |
偶联 | Unconjugated |
免疫原 | Recombinant Protein |
Uniprot ID |
分子量 | Theoretical: 102 kDa. |
储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
运输方式 | Shipping with blue ice. |
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