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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-Dopamine D4 receptor Polyclonal Antibody

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货号 TMAB-05288

Anti-Dopamine D4 receptor Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Dopamine D4 receptor。Anti-Dopamine D4 receptor Polyclonal Antibody 可用于 WB。

Anti-Dopamine D4 receptor Polyclonal Antibody

Anti-Dopamine D4 receptor Polyclonal Antibody

一键复制产品信息
Rating icon 还可以
货号 TMAB-05288

Anti-Dopamine D4 receptor Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Dopamine D4 receptor。Anti-Dopamine D4 receptor Polyclonal Antibody 可用于 WB。

规格价格库存数量
50 μL
¥ 1,175
5日内发货
100 μL
¥ 1,970
5日内发货
200 μL
¥ 2,785
5日内发货
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产品介绍

生物活性
产品描述
Anti-Dopamine D4 receptor Polyclonal Antibody is a Rabbit antibody targeting Dopamine D4 receptor. Anti-Dopamine D4 receptor Polyclonal Antibody can be used in WB.
Ig Type
IgG
反应种属
Human,Mouse (predicted:Rat)
应用WB
推荐剂量
WB: 1:500-2000
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Cell membrane; Multi-pass membrane protein
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景Members of the G protein-coupled receptor family are distinguished by their slow transmitting response to ligand binding. These seven- transmembrane proteins include the adrenergic, serotonin and dopamine receptors. The effect of the signaling molecule can be excitatory or inhibitory depending on the type of receptor to which it binds. b-adrenergic receptor binds to adrenaline and activates adenylyl cyclase, while a2-adrenergic receptor binds to adrenaline and inhibits adenylyl cyclase. The dopamine receptors are divided into two classes, D1 and D2, which differ in their functional characteristics in that D1 receptors stimulate adenylyl cyclase, while D2 receptors inhibit adenylyl cyclase activity. Five different subtypes of dopamine receptor have been described to date. D1DR and D5DR belong to the D1 subclass, while D2DR, D3DR and D4DR belong to the D2 subclass of dopamine receptors.
抗原信息
免疫原
KLH conjugated synthetic peptide: human DRD4
抗原种属
Human
基因名称
DRD4
基因ID
1815
蛋白名称
D(4) dopamine receptor
Uniprot ID
P21917
功能
This gene encodes the D4 subtype of the dopamine receptor. The D4 subtype is a G-protein coupled receptor which inhibits adenylyl cyclase. It is a target for drugs which treat schizophrenia and Parkinson disease. Mutations in this gene have been associated with various behavioral phenotypes, including autonomic nervous system dysfunction, attention deficit/hyperactivity disorder, and the personality trait of novelty seeking. This gene contains a polymorphic number (2-10 copies) of tandem 48 nt repeats; the sequence shown contains four repeats.DRD4 expression has been reported in various regions of the brain as well as in adrenal gland, artery, eye, heart, kidney, placenta, spinal cord, testis, and vas deferens.
化学信息
分子量Theoretical: 41 (mouse/rat); 51 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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