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Anti-DLG4 Antibody (7Y949)
还可以产品编号 TMAH-00350
Anti-DLG4 Antibody (7Y949) 是一种抗体，靶向 DLG4。Anti-DLG4 Antibody (7Y949) 可用于 ELISA, WB。
Anti-DLG4 Antibody (7Y949)
Anti-DLG4 Antibody (7Y949)
还可以产品编号 TMAH-00350
Anti-DLG4 Antibody (7Y949) 是一种抗体，靶向 DLG4。Anti-DLG4 Antibody (7Y949) 可用于 ELISA, WB。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,305 | 5日内发货 | |
| 100 μL | ¥ 2,185 | 5日内发货 |
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产品介绍
生物活性
偶联与修饰
抗原信息
| 产品描述 | Anti-DLG4 Antibody (7Y949) is an antibody targeting DLG4. Anti-DLG4 Antibody (7Y949) can be used in ELISA, WB. |
| Ig Type | Rabbit IgG |
| 克隆号 | 7Y949 |
| 交叉反应 | Human, Mouse, Rat |
| 验证活性 | Western Blot -Positive WB detected in: Rat Brain whole cell lysate, Mouse Brain whole cell lysate -All lanes: PSD95 antibody at 1:1000 -Secondary: Goat polyclonal to rabbit IgG at 1/50000 dilution -Predicted band size: 81, 86, 81 kDa -Observed band size: 95 kDa |
| 应用 | ELISA, WB |
| 推荐剂量 | WB:1:500-1:5000. |
| 抗体种类 | Monoclonal |
| 亚细胞定位 | Cell membrane; Lipid-anchor; Cytoplasmic side. Cell junction, synapse, postsynaptic density. Cell junction, synapse. Cytoplasm. Cell projection, axon. Cell projection, dendritic spine. Cell projection, dendrite. Cell junction, synapse, presynapse. |
| 构建方式 | Recombinant Antibody |
| 纯化方式 | Affinity-chromatography |
| 性状 | Liquid |
| 缓冲液 | Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| 研究背景 | Postsynaptic scaffolding protein that plays a critical role in synaptogenesis and synaptic plasticity by providing a platform for the postsynaptic clustering of crucial synaptic proteins. Interacts with the cytoplasmic tail of NMDA receptor subunits and shaker-type potassium channels. Required for synaptic plasticity associated with NMDA receptor signaling. Overexpression or depletion of DLG4 changes the ratio of excitatory to inhibitory synapses in hippocampal neurons. May reduce the amplitude of ASIC3 acid-evoked currents by retaining the channel intracellularly. May regulate the intracellular trafficking of ADR1B. Also regulates AMPA-type glutamate receptor (AMPAR) immobilization at postsynaptic density keeping the channels in an activated state in the presence of glutamate and preventing synaptic depression. |
| 偶联 | Unconjugated |
| 免疫原 | A synthetic peptide: Human PSD95 |
| 抗原种属 | Human |
| 基因ID | 1742 |
| Uniprot ID | |
| 研究领域 | Neuroscience |
存储&运输
| 储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
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