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Anti-HAAO Polyclonal Antibody

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货号 TMAB-06869

Anti-HAAO Polyclonal Antibody 是一种 Rabbit 抗体,靶向 HAAO。Anti-HAAO Polyclonal Antibody 可用于 WB。

Anti-HAAO Polyclonal Antibody

Anti-HAAO Polyclonal Antibody

一键复制产品信息
Rating icon 还可以
货号 TMAB-06869

Anti-HAAO Polyclonal Antibody 是一种 Rabbit 抗体,靶向 HAAO。Anti-HAAO Polyclonal Antibody 可用于 WB。

规格价格库存数量
50 μL
¥ 1,165
5日内发货
100 μL
¥ 1,975
5日内发货
200 μL
¥ 2,790
5日内发货
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产品介绍


生物活性
产品描述
Anti-HAAO Polyclonal Antibody is a Rabbit antibody targeting HAAO. Anti-HAAO Polyclonal Antibody can be used in WB.
Ig Type
IgG
反应种属
Mouse (predicted:Human,Rat,Pig,Cow,Rabbit,Sheep)
应用WB
推荐剂量
WB: 1:500-2000
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Cytoplasm.
构建方式Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景The 3-HAO family of proteins consists of intramolecular dioxygenases that contain non-heme ferrous iron. HAAO (3-hydroxyanthranilate 3,4-dioxygenase), also known as HAO or 3-HAO, is a 286 amino acid monomeric cytoplasmic protein that belongs to the 3-HAO family. Utilizing Fe2+ ions as a cofactor, HAAO participates in the formation of quinolinic acid (QUIN), and excitotoxin, by catalyzing the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde. HAAO may play a role in disorders that are associated with varying levels of QUIN expression, and is widely expressed in peripheral organs, including kidney and liver. Existing as two alternatively spliced isoforms, the gene encoding HAAO maps to human chromosome 2p21 and mouse chromosome 17 E4.
抗原信息
免疫原
KLH conjugated synthetic peptide: human HAAO
抗原种属
Human
基因名称
HAAO
基因ID
蛋白名称
3-hydroxyanthranilate 3, 4-dioxygenase
Uniprot ID
功能
Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate.
化学信息
分子量Theoretical: 33 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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