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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-DKK1 Polyclonal Antibody

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货号 TMAB-05175

Anti-DKK1 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 DKK1。Anti-DKK1 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

Anti-DKK1 Polyclonal Antibody

Anti-DKK1 Polyclonal Antibody

一键复制产品信息
Rating icon 还可以
货号 TMAB-05175

Anti-DKK1 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 DKK1。Anti-DKK1 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,160
5日内发货
100 μL
¥ 1,965
5日内发货
200 μL
¥ 2,795
5日内发货
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产品介绍

生物活性
产品描述
Anti-DKK1 Polyclonal Antibody is a Rabbit antibody targeting DKK1. Anti-DKK1 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
反应种属
Dog (predicted:Human,Mouse,Rat)
应用IHC-PIHC-FrIF
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Secreted.
组织特异性Placenta.
构建方式Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景This gene encodes a protein that is a member of the dickkopf family. It is a secreted protein with two cysteine rich regions and is involved in embryonic development through its inhibition of the WNT signaling pathway. Elevated levels of DKK1 in bone marrow plasma and peripheral blood is associated with the presence of osteolytic bone lesions in patients with multiple myeloma. [provided by RefSeq, Jul 2008]
抗原信息
免疫原
KLH conjugated synthetic peptide: human DKK1
抗原种属
Human
基因名称
DKK1
基因ID
22943
蛋白名称
Dickkopf-related protein 1
Uniprot ID
O94907
功能
Antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero-posterior axial patterning, limb development, somitogenesis and eye formation. In the adult, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer disease.
化学信息
分子量Theoretical: 29 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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