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Anti-IFNAR1 Antibody (1R657)
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产品编号 TMAC-02087
别名 interferon (α, β and ω) receptor 1, interferon (α, β and Ω) receptor 1, interferon (alpha, beta and omega) receptor 1
Anti-IFNAR1 Antibody (1R657) 是一种 Rabbit 抗体，靶向 IFNAR1。Anti-IFNAR1 Antibody (1R657) 可用于 WB,IP,IHC,FCM。
Anti-IFNAR1 Antibody (1R657)
Anti-IFNAR1 Antibody (1R657)
还可以产品编号 TMAC-02087 别名 interferon (α, β and ω) receptor 1, interferon (α, β and Ω) receptor 1, interferon (alpha, beta and omega) receptor 1
Anti-IFNAR1 Antibody (1R657) 是一种 Rabbit 抗体，靶向 IFNAR1。Anti-IFNAR1 Antibody (1R657) 可用于 WB,IP,IHC,FCM。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,490 | 5日内发货 | |
| 100 μL | ¥ 2,495 | 5日内发货 |
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产品介绍
生物活性
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抗原信息
化学信息
| 产品描述 | Anti-IFNAR1 Antibody (1R657) is a Rabbit antibody targeting IFNAR1. Anti-IFNAR1 Antibody (1R657) can be used in WB,IP,IHC,FCM. |
| 别名 | interferon (α, β and ω) receptor 1, interferon (α, β and Ω) receptor 1, interferon (alpha, beta and omega) receptor 1 |
| Ig Type | IgG |
| 交叉反应 | Human,Mouse,Rat |
| 验证活性 | 1. Immunohistochemical analysis of paraffin-embedded human tonsil tissue using anti-IFNAR1 antibody. Counter stained with hematoxylin. 2. Immunohistochemical analysis of paraffin-embedded human spleen tissue using anti-IFNAR1 antibody. Counter stained with hematoxylin. 3. Immunohistochemical analysis of paraffin-embedded rat brain tissue using anti-IFNAR1 antibody. Counter stained with hematoxylin. 4. Immunohistochemical analysis of paraffin-embedded mouse brain tissue using anti-IFNAR1 antibody. Counter stained with hematoxylin. 5. Flow cytometric analysis of Jurkat cells with IFNAR1 antibody at 1/50 dilution (blue) compared with an unlabelled control (cells without incubation with primary antibody; red). Alexa Fluor 488-conjugated goat anti rabbit IgG was used as the secondary antibody. |
| 应用 | |
| 推荐剂量 | WB: 1:1000-2000; IHC: 1:50-200; FCM: 1:50-100 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 构建方式 | Recombinant Antibody |
| 纯化方式 | ProA affinity purified |
| 性状 | Liquid |
| 缓冲液 | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| 研究背景 | The type I interferons (IFNs), α and β, are a group of structurally and functionally related proteins that are induced by either viruses or double stranded RNA and defined by their ability to confer an antiviral state in cells. The α and β IFNs appear to compete with one another for binding to a common cell surface receptor, while immune IFN (IFNγ) binds to a distinct receptor. The latter protein, IFN-αR, is only weakly responsive to type I interferons in contrast to IFN-α/βR, which binds to and responds effectively to IFN-β and to several of the IFN-? subtypes. Moreover, IFN-α/βR is physically associated with the cytoplasmic tyrosine kinase JAK1 and thus, in addition to ligand binding, appears to be functionally involved in signal transduction. IFN-αR1 is a receptor for IFN-α/β and is present as the full chain (IFN-αR1a) and as a splice-variant (IFN-αR1). The IFN-γ receptor complex consists of an alpha subunit (IFN-γRα) and a beta subunit that is 332 amino acids in length (mouse) and 337 amino acids in length (human). |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Protein |
| Uniprot ID |
| 分子量 | Theoretical: 90/130 kDa. |
存储&运输
| 储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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