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Anti-CARD11 Antibody (9H360) 是一种 Rabbit 抗体,靶向 CARD11。Anti-CARD11 Antibody (9H360) 可用于 WB,ICC/IF,FCM。
Anti-CARD11 Antibody (9H360) 是一种 Rabbit 抗体,靶向 CARD11。Anti-CARD11 Antibody (9H360) 可用于 WB,ICC/IF,FCM。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 25 μL | ¥ 795 | 5日内发货 | |
| 50 μL | ¥ 1,390 | 5日内发货 | |
| 100 μL | ¥ 2,495 | 5日内发货 |
| 产品描述 | Anti-CARD11 Antibody (9H360) is a Rabbit antibody targeting CARD11. Anti-CARD11 Antibody (9H360) can be used in WB,ICC/IF,FCM. |
| Ig Type | IgG |
| 克隆号 | 9H360 |
| 反应种属 | Human,Mouse |
| 应用 | WBICC/IFFCM |
| 推荐剂量 | WB: 1:500-2000; ICC/IF: 1:50-200; FCM: 1:50-100 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 亚细胞定位 | Cytoplasm. Membrane raft. Note=Colocalized with DPP4 in membrane rafts. |
| 组织特异性 | Detected in adult peripheral blood leukocytes, thymus, spleen and liver. Also found in promyelocytic leukemia HL-60 cells, chronic myelogenous leukemia K-562 cells, Burkitt's lymphoma Raji cells and colorectal adenocarcinoma SW480 cells. Not detected in HeLaS3, MOLT-4, A-549 and G431 cells. |
| 构建方式 | Recombinant Antibody |
| 纯化方式 | Protein A purified |
| 性状 | Liquid |
| 缓冲液 | 10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol. |
| 研究背景 | Adapter protein that plays a key role in adaptive immune response by transducing the activation of NF-kappa-B downstream of T-cell receptor (TCR) and B-cell receptor (BCR) engagement.Transduces signals downstream TCR or BCR activation via the formation of a multiprotein complex together with BCL10 and MALT1 that induces NF-kappa-B and MAP kinase p38. |
| 免疫原 | A synthesized peptide: human CARD11 |
| 抗原种属 | Human |
| 基因名称 | CARD11 |
| 基因ID | |
| 蛋白名称 | Caspase recruitment domain-containing protein 11 |
| Uniprot ID | |
| 功能 | Involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependent manner. Activates NF-kappa-B via BCL10 and IKK. Stimulates the phosphorylation of BCL10. |
| 分子量 | Theoretical: 133 kDa. Actual: 133 kDa. |
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
| 存储 | store at low temperature | -20°C for 1 year |