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Anti-CD21 Antibody-FITC (2N104) 是一种 FITC-conjugated Mouse 抗体,靶向 CD21。Anti-CD21 Antibody-FITC (2N104) 可用于 FCM。
Anti-CD21 Antibody-FITC (2N104) 是一种 FITC-conjugated Mouse 抗体,靶向 CD21。Anti-CD21 Antibody-FITC (2N104) 可用于 FCM。
产品描述 | Anti-CD21 Antibody-FITC (2N104) is a FITC-conjugated Mouse antibody targeting CD21. Anti-CD21 Antibody-FITC (2N104) can be used in FCM. |
Ig Type | Monoclonal Mouse IgG1 |
克隆号 | 2N104 |
交叉反应 | Human |
验证活性 | Flow cytometric analysis of Human CD21 expression on human whole blood lymphocytes. Cells were stained with FITC-conjugated anti-Human CD21 and APC-conjugated anti-Human CD19. The dot plots were derived from gated events with the forward and side light-scatter characteristics of viable lymphocytes. |
应用 | FCM |
推荐剂量 | 5 μl/Test, 0.1 mg/ml |
抗体种类 | Monoclonal |
宿主来源 | Mouse |
构建方式 | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human CD21 (rh CD21; P20023-1Met1-Arg971) and conjugated with FITC under optimum conditions, the unreacted FITC was removed. |
纯化方式 | Protein A |
性状 | Liquid |
缓冲液 | PBS solution containing 0.5% BSA and 0.09% sodium azide |
研究背景 | The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immune function of the cell. There are more than 320 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alter the behavior of the cell. Some CD proteins do not take part in cell signal process but have other functions such as cell adhesion. CD21, also known as Complement component (3d / Epstein Barr virus) receptor 2 and CR2, is a member of the CD system and is a protein involved in complement system. CD21 is present on all mature B-cells and some T-cells and follicular dendritic cells. CD21 on mature B-cells form a complex called the B cell receptor complex with two other membrane proteins, CD19 and CD81. CD21 has a function in the complement system through serving as the cellular receptor specific for ligands such as C3 and C4 which can be attached to foreign macromolecules in order to remove or uptake them. This results in B-cells having enhanced response to the antigen. |
偶联 | FITC |
其他可选修饰符 | Unconjugated/APC/PE |
可提供抗体种类 | 4 |
免疫原 | Recombinant Human CD21 Protein |
抗原种属 | Human |
研究领域 | Serine Proteases and Regulators |
储存方式 | Store at 2°C-8°C for 12 months, do not freeze. Keep away from direct sunlight. Sodium azide is toxic to cells and should be disposed of properly. Flush with large volumes of water during disposal. |
运输方式 | Shipping with blue ice. |
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