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4-1BB/CD137/TNFRSF9 Protein, Human, Recombinant (hFc & His)

Synonyms: TNFRSF9, T-cell antigen ILA, T-cell antigen 4-1BB homolog, ILA, CDw137, CD137, 4-1BB ligand receptor
货号 TMPJ-00144 一键复制产品信息
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Tumor necrosis factor receptor superfamily member 9(TNFRSF9) is an inducible T cell surface protein belonging to the TNF receptor superfamily. It is a single-pass type I membrane protein which contains 4 TNFR-Cys repeats. The human and mouse proteins share 60% amino acid sequence identity. It is absent from naive T cells, but upregulated and continually expressed following T cell activation. It is a receptor for TNFSF9/4-1BBL, and possibly active during T cell activation. 4-1BB/CD137/TNFRSF9 Protein, Human, Recombinant (hFc & His) is expressed in HEK293 mammalian cells with C-Fc-6xHis tag. The predicted molecular weight is 55-75 KDa and the accession number is Q07011.

4-1BB/CD137/TNFRSF9 Protein, Human, Recombinant (hFc & His)

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货号 TMPJ-00144

别名 TNFRSF9, T-cell antigen ILA, T-cell antigen 4-1BB homolog, ILA, CDw137, CD137, 4-1BB ligand receptor

Tumor necrosis factor receptor superfamily member 9(TNFRSF9) is an inducible T cell surface protein belonging to the TNF receptor superfamily. It is a single-pass type I membrane protein which contains 4 TNFR-Cys repeats. The human and mouse proteins share 60% amino acid sequence identity. It is absent from naive T cells, but upregulated and continually expressed following T cell activation. It is a receptor for TNFSF9/4-1BBL, and possibly active during T cell activation. 4-1BB/CD137/TNFRSF9 Protein, Human, Recombinant (hFc & His) is expressed in HEK293 mammalian cells with C-Fc-6xHis tag. The predicted molecular weight is 55-75 KDa and the accession number is Q07011.

4-1BB/CD137/TNFRSF9 Protein, Human, Recombinant (hFc & His)
规格价格库存数量
5 μg
¥ 479
6-8日内发货
10 μg
¥ 780
6-8日内发货
20 μg
¥ 1,070
5日内发货
50 μg
¥ 1,650
5日内发货
100 μg
¥ 2,830
5日内发货
200 μg
¥ 4,890
5日内发货
500 μg
¥ 10,200
5日内发货
1 mg
¥ 16,600
5日内发货
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产品介绍


生物活性
产品描述
Tumor necrosis factor receptor superfamily member 9(TNFRSF9) is an inducible T cell surface protein belonging to the TNF receptor superfamily. It is a single-pass type I membrane protein which contains 4 TNFR-Cys repeats. The human and mouse proteins share 60% amino acid sequence identity. It is absent from naive T cells, but upregulated and continually expressed following T cell activation. It is a receptor for TNFSF9/4-1BBL, and possibly active during T cell activation. 4-1BB/CD137/TNFRSF9 Protein, Human, Recombinant (hFc & His) is expressed in HEK293 mammalian cells with C-Fc-6xHis tag. The predicted molecular weight is 55-75 KDa and the accession number is Q07011.
生物活性
1. Loaded Human 4-1BB-Fc-His on HIS1K Biosensor, can bind Anti-Human CD137 mAb with an affinity constant of 12.2 nM as determined in BLI assay. (Regularly tested) 2. Immobilized Human 4-1BB-Fc-His at 2μg/ml (100 μl/well)can bind Anti-Human CD137 mAb. The ED50 of Anti-Human CD137 mAb is 0.41ug/ml. (Regularly tested)
研究背景
Tumor necrosis factor receptor superfamily member 9(TNFRSF9) is an inducible T cell surface protein belonging to the TNF receptor superfamily. It is a single-pass type I membrane protein which contains 4 TNFR-Cys repeats. The human and mouse proteins share 60% amino acid sequence identity. It is absent from naive T cells, but upregulated and continually expressed following T cell activation. It is a receptor for TNFSF9/4-1BBL, and possibly active during T cell activation.
种属
Human
表达系统
HEK293 Cells
标签C-hFc-6xHis
蛋白编号Q07011
氨基酸序列Leu24-Gln186
蛋白构建Leu24-Gln186
缓冲液Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4.
复溶方法Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
别名TNFRSF9, T-cell antigen ILA, T-cell antigen 4-1BB homolog, ILA, CDw137, CD137, 4-1BB ligand receptor
内毒素< 0.1 ng/µg (1 EU/µg) as determined by LAL test.
化学信息
分子量55-75 KDa (reducing condition)
储存&溶解度
运输方式In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
存储

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