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4-1BB/CD137/TNFRSF9 Protein, Human, Recombinant (hFc & His)
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货号 TMPJ-00144
别名 TNFRSF9, T-cell antigen ILA, T-cell antigen 4-1BB homolog, ILA, CDw137, CD137, 4-1BB ligand receptor
Tumor necrosis factor receptor superfamily member 9(TNFRSF9) is an inducible T cell surface protein belonging to the TNF receptor superfamily. It is a single-pass type I membrane protein which contains 4 TNFR-Cys repeats. The human and mouse proteins share 60% amino acid sequence identity. It is absent from naive T cells, but upregulated and continually expressed following T cell activation. It is a receptor for TNFSF9/4-1BBL, and possibly active during T cell activation. 4-1BB/CD137/TNFRSF9 Protein, Human, Recombinant (hFc & His) is expressed in HEK293 mammalian cells with C-Fc-6xHis tag. The predicted molecular weight is 55-75 KDa and the accession number is Q07011.
其他形式的 “4-1BB/CD137/TNFRSF9 Protein, Human, Recombinant (hFc & His)”:
4-1BB/CD137/TNFRSF9 Protein, Human, Recombinant (hFc & His)
一键复制产品信息 还可以SPR兼容缓冲液
货号 TMPJ-00144 别名 TNFRSF9, T-cell antigen ILA, T-cell antigen 4-1BB homolog, ILA, CDw137, CD137, 4-1BB ligand receptor
Tumor necrosis factor receptor superfamily member 9(TNFRSF9) is an inducible T cell surface protein belonging to the TNF receptor superfamily. It is a single-pass type I membrane protein which contains 4 TNFR-Cys repeats. The human and mouse proteins share 60% amino acid sequence identity. It is absent from naive T cells, but upregulated and continually expressed following T cell activation. It is a receptor for TNFSF9/4-1BBL, and possibly active during T cell activation. 4-1BB/CD137/TNFRSF9 Protein, Human, Recombinant (hFc & His) is expressed in HEK293 mammalian cells with C-Fc-6xHis tag. The predicted molecular weight is 55-75 KDa and the accession number is Q07011.
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 5 μg | ¥ 479 | 6-8日内发货 | |
| 10 μg | ¥ 780 | 6-8日内发货 | |
| 20 μg | ¥ 1,070 | 5日内发货 | |
| 50 μg | ¥ 1,650 | 5日内发货 | |
| 100 μg | ¥ 2,830 | 5日内发货 | |
| 200 μg | ¥ 4,890 | 5日内发货 | |
| 500 μg | ¥ 10,200 | 5日内发货 | |
| 1 mg | ¥ 16,600 | 5日内发货 |
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| 产品描述 | Tumor necrosis factor receptor superfamily member 9(TNFRSF9) is an inducible T cell surface protein belonging to the TNF receptor superfamily. It is a single-pass type I membrane protein which contains 4 TNFR-Cys repeats. The human and mouse proteins share 60% amino acid sequence identity. It is absent from naive T cells, but upregulated and continually expressed following T cell activation. It is a receptor for TNFSF9/4-1BBL, and possibly active during T cell activation. 4-1BB/CD137/TNFRSF9 Protein, Human, Recombinant (hFc & His) is expressed in HEK293 mammalian cells with C-Fc-6xHis tag. The predicted molecular weight is 55-75 KDa and the accession number is Q07011. |
| 生物活性 | 1. Loaded Human 4-1BB-Fc-His on HIS1K Biosensor, can bind Anti-Human CD137 mAb with an affinity constant of 12.2 nM as determined in BLI assay. (Regularly tested)
2. Immobilized Human 4-1BB-Fc-His at 2μg/ml (100 μl/well)can bind Anti-Human CD137 mAb. The ED50 of Anti-Human CD137 mAb is 0.41ug/ml. (Regularly tested) |
| 研究背景 | Tumor necrosis factor receptor superfamily member 9(TNFRSF9) is an inducible T cell surface protein belonging to the TNF receptor superfamily. It is a single-pass type I membrane protein which contains 4 TNFR-Cys repeats. The human and mouse proteins share 60% amino acid sequence identity. It is absent from naive T cells, but upregulated and continually expressed following T cell activation. It is a receptor for TNFSF9/4-1BBL, and possibly active during T cell activation. |
| 种属 | Human |
| 表达系统 | HEK293 Cells |
| 标签 | C-hFc-6xHis |
| 蛋白编号 | Q07011 |
| 氨基酸序列 | Leu24-Gln186 |
| 蛋白构建 | Leu24-Gln186 |
| 缓冲液 | Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4. |
| 复溶方法 | Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing. |
| 别名 | TNFRSF9, T-cell antigen ILA, T-cell antigen 4-1BB homolog, ILA, CDw137, CD137, 4-1BB ligand receptor |
| 内毒素 | < 0.1 ng/µg (1 EU/µg) as determined by LAL test. |
| 分子量 | 55-75 KDa (reducing condition) |
| 运输方式 | In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice. |
| 存储 | Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
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