Name: PSB-1114 tetrasodium
Brand: TargetMol
SKU: T16672
Rating: 4.5 (1 reviews)

规格

价格

库存

数量

500 μg

¥ 8,260

35日内发货

生物活性

产品描述	PSB-1114 tetrasodium shows >50-fold selectivity versus the P2Y4 (EC50: 9.3 μM) and P2Y6 (EC50: 7.0 μM) receptors. PSB-1114 tetrasodium is an effective, enzymatically stable, and subtype-selective P2Y2 receptor agonist (EC50: 134 nM) .
靶点活性	P2Y2 receptor:（EC50）134 nM, P2Y6 receptor:7.0 μM（EC50）, P2Y4 receptor:9.3 μM（EC50）
体外活性	PSB-1114 may be a useful pharmacological tool for studying P2Y2 receptors. PSB-1114 (4-Thio-β,γ-difluoromethylene-UTP) shows >60-fold selectivity versus P2Y4 and P2Y6 receptors. Because of its high potency, selectivity, and expected metabolic stability toward ectonucleotidases, in particular NTPDases [1].

化学信息

分子量	626.17
分子式	C₁₀H₁₅F₂N₂Na₄O₁₃P₃S
CAS No.	1657025-60-9
Smiles	[Na].[Na].[Na].[Na].O[C@H]1[C@@H](O)[C@@H](O[C@@H]1COP(O)(=O)OP(O)(=O)C(F)(F)P(O)(O)=O)n1ccc(=S)[nH]c1=OjcExt:v:0:0,1:0,2:0,3:0
密度	no data available