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Anti-KRT5 Antibody (5H465)

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Anti-KRT5 Antibody (5H465)
产品编号 TMAY-00122
别名 KRT5A, K5, EBS2F, EBS2E, EBS2D, EBS2C, EBS2B, EBS2A, EBS2, EBS1, DDD1, DDD, CK-5, CK5

Anti-KRT5 Antibody (5H465) 是一种 Mouse 抗体,靶向 KRT5。Anti-KRT5 Antibody (5H465) 可用于 WB。

Anti-KRT5 Antibody (5H465)

Anti-KRT5 Antibody (5H465)

Rating icon 还可以
Anti-KRT5 Antibody (5H465)
产品编号 TMAY-00122 别名 KRT5A, K5, EBS2F, EBS2E, EBS2D, EBS2C, EBS2B, EBS2A, EBS2, EBS1, DDD1, DDD, CK-5, CK5

Anti-KRT5 Antibody (5H465) 是一种 Mouse 抗体,靶向 KRT5。Anti-KRT5 Antibody (5H465) 可用于 WB。

规格价格库存数量
100 μL
¥ 1,679
5日内发货
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产品介绍

生物活性
产品描述
Anti-KRT5 Antibody (5H465) is a Mouse antibody targeting KRT5. Anti-KRT5 Antibody (5H465) can be used in WB.
别名KRT5A, K5, EBS2F, EBS2E, EBS2D, EBS2C, EBS2B, EBS2A, EBS2, EBS1, DDD1, DDD, CK-5, CK5
Ig Type
Mouse IgG1
克隆号
5H465
交叉反应
Human
验证活性
Anti-KRT5 mouse monoclonal antibody at 1:500 dilution.
-Lane A: A431 Whole Cell lysate.
-Lysates/proteins at 30 μg per lane.
-Secondary
-Goat Anti-Mouse IgG H&L (Dylight800) at 1/15000 dilution.
-Developed using the Odyssey technique.
-Performed under reducing conditions.
-Predicted band size:62 kDa.
-Observed band size:62 kDa
应用
推荐剂量
WB: 1:500-1:2000
抗体种类
Monoclonal
宿主来源Mouse
构建方式This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with a synthetic peptide corresponding to the center region of the human KRT5. The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.
纯化方式Protein A
性状Liquid
缓冲液0.2 μm filtered solution in PBS
研究背景Keratin 5 is the major type II keratin of the basal cells of the epidermis and other stratified epithelia. With its type I partner, keratin 14, it constitutes a major fraction of the cytoskeleton of the basal cells. Epidermolysis bullosa simplex with mottled pigmentation (EBS-MP) is a rare dermatologic disorder of autosomal dominant inheritance with intraepidermal blistering after minor trauma, reticular hyperpigmentation unrelated to the blistering, nail dystrophy, and mild palmoplantar keratosis. Keratin 5 and keratin 14 are known to be essential for the basal keratinocyte cytoskeleton and are defective in several forms of epidermolysis bullosa simplex. Recently, a 71C-->T transition in the keratin 5 gene (KRT5) causing a P24L substitution was identified in some patients with EBS-MP.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
A synthetic peptide: center region of the human KRT5
抗原种属
Human
存储&运输
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
运输方式Shipping with blue ice.

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