Name: Anti-Mouse CD16.2 Antibody (9E9)
Brand: TargetMol
SKU: T9901A-1170
Rating: 4.5 (1 reviews)

规格

价格

库存

数量

1 mg

¥ 1,820

待询

5 mg

¥ 4,430

待询

10 mg

待询

生物活性

产品描述	Anti-Mouse CD16.2 Antibody (9E9) is an inhibitory antibody derived from Armenian hamster, targeting mouse CD16.2.This antibody can bind to mouse CD16.2, which is also known as FcγRIV (Fc receptor, IgG, low affinity IV).Anti-Mouse CD16.2 Antibody (9E9) can inhibit the expression and signaling of CD16.2 on the cell surface and block FcγRIV.This antibody is applicable to studies related to cancer, inflammation and immunology, including CT26 tumor models and pulmonary inflammation .
体外活性	Anti-Mouse CD16.2 Antibody (9E9)（10 μg/mL）能够抑制 MH‑S 细胞内由 IgE 免疫复合物诱导产生的 TNF‑α 分泌 [1]。
体内活性	Anti-Mouse CD16.2 Antibody (9E9)（于硫代乙醇酸盐诱导的巨噬细胞采集前 1 天静脉注射）能够抑制 hFcεRITg 小鼠体内约 25% 的巨噬细胞 TNF-α 分泌 [1]。 Anti-Mouse CD16.2 Antibody (9E9)（200 μg，腹腔注射，分别在第 0、4、8 天给药）可缓解大疱性类天疱疮小鼠的皮肤损伤症状 [2]。 Anti-Mouse CD16.2 Antibody (9E9)（200 μg，于抗 CTLA4 注射前 1 小时静脉给药）能够阻断 CT26 肿瘤小鼠中由抗 CTLA4 介导的调节性 T 细胞耗竭 [3]。
别名	抗小鼠 CD16.2 抗体 (9E9)
克隆号	9E9
反应种属	Mouse
应用	ELISA FCM Functional assay
抗体种类	Monoclonal
缓冲液	Supplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition.
内毒素	<1.0 EU/mg

抗体信息

同型	Armenian hamster IgG
推荐同型对照	Armenian hamster IgG, Isotype Control

偶联与修饰

偶联	Unconjugated

抗原信息

化学信息

分子量

150 kDa

储存&溶解度

存储

Anti-Mouse CD16.2 Antibody (9E9)