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Anti-NACC1 Antibody (6F944) 是一种 Mouse 抗体,靶向 NACC1。Anti-NACC1 Antibody (6F944) 可用于 WB,IHC。
Anti-NACC1 Antibody (6F944) 是一种 Mouse 抗体,靶向 NACC1。Anti-NACC1 Antibody (6F944) 可用于 WB,IHC。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
50 μL | ¥ 1,995 | 5日内发货 | |
100 μL | ¥ 2,985 | 5日内发货 |
产品描述 | Anti-NACC1 Antibody (6F944) is a Mouse antibody targeting NACC1. Anti-NACC1 Antibody (6F944) can be used in WB,IHC. |
别名 | Nucleus accumbens-associated protein 1, NACC1_HUMAN, Nacc 1, NAC-1, NAC1, FLJ37383, btbd14b, BTB/POZ domain-containing protein 14B, BTB Domain Containing 14B, BEND8 |
交叉反应 | Human |
验证活性 | 1. Western blot analysis of NACC1 on HEK293 (1) and NACC1-hIgGFc transfected HEK293 (2) cell lysate using anti-NACC1 antibody at 1/1,000 dilution. 2. Immunohistochemical analysis of paraffin-embedded human mammary cancer tissue using anti-NACC1 antibody. Counter stained with hematoxylin. 3. Immunohistochemical analysis of paraffin-embedded human ovarian cancer tissue using anti-NACC1 antibody. Counter stained with hematoxylin. |
应用 | |
推荐剂量 | WB: 1:500-1000; IHC: 1:100-500 |
抗体种类 | Monoclonal |
宿主来源 | Mouse |
构建方式 | Hybridoma Monoclonal Antibody |
纯化方式 | ProA affinity purified |
性状 | Liquid |
缓冲液 | 1*TBS (pH7.4), 1%BSA, Preservative: 0.05% Sodium Azide. |
研究背景 | The BTB (broad-complex, Tramtrack and Bric a brac) domain, also known as the POZ (Poxvirus and zinc finger) domain, is an N-terminal homodimerization domain that contains multiple copies of kelch repeats and/or C2H2-type zinc fingers. Proteins that contain BTB domains are thought to be involved in transcriptional regulation via control of chromatin structure and function. BTBD14B (BTB/POZ domain-containing protein 14B), also known as NACC1 (nucleus accumbens associated 1), BEND8 or NAC1, is a 527 amino acid protein that localizes to both the nucleus and the cytoplasm and contains one BTB (POZ) domain. Existing as a homooligomer that interacts with HDAC3 and HDAC4, BTBD14B functions as a transcriptional repressor that influences the transcriptional activity of CRIF1 and is required for proteasome recruitment to the nucleus and cytoplasm in dendritic spines. BTBD14B is overexpressed in multiple carcinomas, suggesting a role in tumor development and metastasis. |
偶联 | Unconjugated |
免疫原 | Recombinant Protein |
Uniprot ID |
分子量 | Theoretical: 58 kDa. |
储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
运输方式 | Shipping with blue ice. |
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