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Anti-IL-2 R gamma/CD132 Antibody-HRP (3Z310) 是一种 HRP-conjugated Rabbit 抗体,靶向 IL-2 R gamma/CD132。Anti-IL-2 R gamma/CD132 Antibody-HRP (3Z310) 可用于 ELISA。
Anti-IL-2 R gamma/CD132 Antibody-HRP (3Z310) 是一种 HRP-conjugated Rabbit 抗体,靶向 IL-2 R gamma/CD132。Anti-IL-2 R gamma/CD132 Antibody-HRP (3Z310) 可用于 ELISA。
产品描述 | Anti-IL-2 R gamma/CD132 Antibody-HRP (3Z310) is a HRP-conjugated Rabbit antibody targeting IL-2 R gamma/CD132. Anti-IL-2 R gamma/CD132 Antibody-HRP (3Z310) can be used in ELISA. |
Ig Type | Monoclonal Rabbit IgG |
克隆号 | 3Z310 |
交叉反应 | Mouse |
应用 | ELISA |
推荐剂量 | ELISA: 0.1-1 μg/ml |
抗体种类 | Monoclonal |
宿主来源 | Rabbit |
构建方式 | This antibody was obtained from a rabbit immunized with purified, recombinant Mouse CD132 / IL2RG (rM CD132 / IL2RG; TMPY-01837; NP_038591.1; Met1-Ala263), and conjugated with horseradish-peroxidase (HRP). |
纯化方式 | Protein A |
性状 | Liquid |
缓冲液 | 0.2 μm filtered solution in PBS |
研究背景 | The common gamma chain (γc) (or CD132), also known as interleukin-2 receptor subunit gamma or IL2RG, is a member of the type I cytokine receptor family expressed on most lymphocyte (white blood cell) populations, and its gene is found on the X-chromosome of mammals. The common gamma chain (γc) (or IL2RG), is a cytokine receptor subunit that is common to the receptor complexes for at least six different interleukin receptors: IL-2, IL-4, IL-7, IL-9, IL-15, and the interleukin-21 receptor. It is a component of multiple cytokine receptors that are essential for lymphocyte development and function. X-linked severe combined immunodeficiency (X-SCID) is a rare and potentially fatal disease caused by mutations of IL2RG, the gene encoding IL2RG. IL2RG was demonstrated to be a component of the IL-4 receptor based on chemical cross-linking data, the ability of IL2RG to augment IL-4 binding affinity. The observation that IL-2R gamma is a functional component of the IL-4 receptor, together with the finding that IL-2R gamma associates with the IL-7 receptor, begins to elucidate why a deficiency of this common gamma chain (gamma c) has a profound effect on lymphoid function and development, as seen in X-linked severe combined immunodeficiency. |
偶联 | HRP |
其他可选修饰符 | Unconjugated |
可提供抗体种类 | 2 |
免疫原 | Recombinant Mouse CD132 / IL2RG protein (TMPY-01837) |
抗原种属 | Mouse |
储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. Keep away from direct sunlight. |
运输方式 | Shipping with blue ice. |
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