Name: HX009
Brand: TargetMol
SKU: T9901A-797
Price: 3290 CNY
Availability: InStock
Rating: 5 (10 reviews)

规格

价格

库存

数量

1 mg

¥ 3,290

现货

5 mg

¥ 9,780

现货

10 mg

¥ 15,600

现货

25 mg

¥ 28,900

现货

生物活性

产品描述	HX009 is a bispecific antibody targeting PD-1 and CD47 (EC50=0.05 nM/0.24 nM). It binds and blocks PD-1 and CD47, selectively localizes to the tumor microenvironment, and reduces hematotoxicity. It can be used to study non-Hodgkin lymphoma (NHL).
靶点活性	PD-1:0.05 nM (EC50), CD47:2.6 nM (EC50)
体内活性	在免疫功能受损的NOD/SCID小鼠皮下Raji异种移植淋巴瘤模型中，HX009（10 mg/kg）诱导了显著的生长延迟（约54% TGI）[1]。
反应种属	Human
应用	ELISA FACS Functional assay
抗体种类	Monoclonal
缓冲液	Supplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition.
内毒素	<1 EU/mg

抗体信息

同型	Human IgG4SP kappa
推荐同型对照	Human IgG4 (S228P) kappa, Isotype Control

偶联与修饰

偶联	Unconjugated

化学信息

分子量	173.16 kDa

储存&溶解度

存储	Store at -80°C Shipping with blue ice. 实际储存温度请以COA为准

HX009