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Anti-Insulin Antibody (9U746)

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产品编号 TMAY-01503

Anti-Insulin Antibody (9U746) 是一种 Mouse 抗体,靶向 Insulin。Anti-Insulin Antibody (9U746) 可用于 IHC-P。

Anti-Insulin Antibody (9U746)

Anti-Insulin Antibody (9U746)

Rating icon 还可以
产品编号 TMAY-01503

Anti-Insulin Antibody (9U746) 是一种 Mouse 抗体,靶向 Insulin。Anti-Insulin Antibody (9U746) 可用于 IHC-P。

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产品介绍

生物活性
产品描述
Anti-Insulin Antibody (9U746) is a Mouse antibody targeting Insulin. Anti-Insulin Antibody (9U746) can be used in IHC-P.
Ig Type
Monoclonal Mouse IgG1
克隆号
9U746
交叉反应
Human
验证活性
Immunochemical staining of human Insulin in human pancreas with mouse monoclonal antibody (1:1000, formalin-fixed paraffin embedded sections).
应用
IHC-P
推荐剂量
IHC-P: 1:500-1:2000
抗体种类
Monoclonal
宿主来源Mouse
构建方式This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human Insulin / INS (rh Insulin / INS; TMPY-00395; P01308; Phe25-Lys53 & Gly90-Asn110). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.
纯化方式Protein A
性状Liquid
缓冲液0.2 μm filtered solution in PBS
研究背景INS (Insulin) is a Protein Coding gene. This gene encodes insulin, a peptide hormone that plays a vital role in the regulation of carbohydrate and lipid metabolism. After removal of the precursor signal peptide, proinsulin is post-translationally cleaved into three peptides: the B chain and A chain peptides, which are covalently linked via two disulfide bonds to form insulin, and C-peptide. The binding of insulin to the insulin receptor (INSR) stimulates glucose uptake. Diseases associated with INS include Hyperproinsulinemia and Maturity-Onset Diabetes Of The Young, Type 10. A multitude of mutant alleles with phenotypic effects has been identified, including insulin-dependent diabetes mellitus, permanent neonatal diabetes mellitus, maturity-onset diabetes of the young type 10, and hyperproinsulinemia.Cancer ImmunotherapyImmune CheckpointImmunotherapyTargeted Therapy
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Human Insulin / INS Protein (TMPY-00395)
抗原种属
Human
存储&运输
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
运输方式Shipping with blue ice.

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