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Anti-ST2/IL-1 RL1 Antibody (6D935) 是一种 Mouse 抗体,靶向 ST2/IL-1 RL1。Anti-ST2/IL-1 RL1 Antibody (6D935) 可用于 ELISA(Cap)。
Anti-ST2/IL-1 RL1 Antibody (6D935) 是一种 Mouse 抗体,靶向 ST2/IL-1 RL1。Anti-ST2/IL-1 RL1 Antibody (6D935) 可用于 ELISA(Cap)。
产品描述 | Anti-ST2/IL-1 RL1 Antibody (6D935) is a Mouse antibody targeting ST2/IL-1 RL1. Anti-ST2/IL-1 RL1 Antibody (6D935) can be used in ELISA(Cap). |
Ig Type | Monoclonal Mouse IgG1 |
克隆号 | 6D935 |
交叉反应 | Human |
应用 | ELISA(Cap) |
抗体种类 | Monoclonal |
宿主来源 | Mouse |
构建方式 | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human IL1RL1 / IL‑1 R4 (rh IL1RL1 / IL‑1 R4; TMPY-01359; NP_003847.2; Met1-Phe328). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
纯化方式 | Protein A |
性状 | Liquid |
缓冲液 | 0.2 μm filtered solution in PBS with 10% Trehalose, pH7.0 |
研究背景 | IL-1 receptor–like 1 (IL1RL1) is a membrane receptor involved in TH2 inflammatory responses and eosinophilia. It has previously been described that levels of the interleukin-1 like 1 (IL1RL1) protein can be used to diagnose cardiovascular disease and determine the prognosis for a patient with cardiovascular disease. The ligand for IL1RL1 has been described and named IL-33. Mutants in IL1RL1 have been associated with blood eosinophil counts in a genome-wide association study and with asthma in family-based and case-control studies. As an important mediator involved in many immune and inflammatory responses, this cytokine has been implicated as a regulator of both the development and effector phases of type 2 helper T cell responses, and as a negative feedback modulator of macrophage proinflammatory function. IL33 is a specific ligand of ST2L and induces the production of Th2 cytokines. |
偶联 | Unconjugated |
免疫原 | Recombinant Human IL1RL1 / IL‑1 R4 Protein (TMPY-01359) |
抗原种属 | Human |
储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
运输方式 | Shipping with blue ice. |
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