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Anti-ST2/IL-1 RL1 Antibody (6D935)

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产品编号 TMAY-00264

Anti-ST2/IL-1 RL1 Antibody (6D935) 是一种 Mouse 抗体,靶向 ST2/IL-1 RL1。Anti-ST2/IL-1 RL1 Antibody (6D935) 可用于 ELISA(Cap)。

Anti-ST2/IL-1 RL1 Antibody (6D935)

Anti-ST2/IL-1 RL1 Antibody (6D935)

Rating icon 还可以
产品编号 TMAY-00264

Anti-ST2/IL-1 RL1 Antibody (6D935) 是一种 Mouse 抗体,靶向 ST2/IL-1 RL1。Anti-ST2/IL-1 RL1 Antibody (6D935) 可用于 ELISA(Cap)。

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产品介绍

生物活性
产品描述
Anti-ST2/IL-1 RL1 Antibody (6D935) is a Mouse antibody targeting ST2/IL-1 RL1. Anti-ST2/IL-1 RL1 Antibody (6D935) can be used in ELISA(Cap).
Ig Type
Monoclonal Mouse IgG1
克隆号
6D935
交叉反应
Human
应用
ELISA(Cap)
抗体种类
Monoclonal
宿主来源Mouse
构建方式This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human IL1RL1 / IL‑1 R4 (rh IL1RL1 / IL‑1 R4; TMPY-01359; NP_003847.2; Met1-Phe328). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.
纯化方式Protein A
性状Liquid
缓冲液0.2 μm filtered solution in PBS with 10% Trehalose, pH7.0
研究背景IL-1 receptor–like 1 (IL1RL1) is a membrane receptor involved in TH2 inflammatory responses and eosinophilia. It has previously been described that levels of the interleukin-1 like 1 (IL1RL1) protein can be used to diagnose cardiovascular disease and determine the prognosis for a patient with cardiovascular disease. The ligand for IL1RL1 has been described and named IL-33. Mutants in IL1RL1 have been associated with blood eosinophil counts in a genome-wide association study and with asthma in family-based and case-control studies. As an important mediator involved in many immune and inflammatory responses, this cytokine has been implicated as a regulator of both the development and effector phases of type 2 helper T cell responses, and as a negative feedback modulator of macrophage proinflammatory function. IL33 is a specific ligand of ST2L and induces the production of Th2 cytokines.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Human IL1RL1 / IL‑1 R4 Protein (TMPY-01359)
抗原种属
Human
存储&运输
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
运输方式Shipping with blue ice.

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