Name: Anti-Mouse CTLA-4/CD152 (LALA-PG) Antibody (9D9)
Brand: TargetMol
SKU: T9901A-848
Rating: 4.5 (1 reviews)

规格

价格

库存

数量

1 mg

¥ 1,820

2-4周

5 mg

¥ 4,430

2-4周

10 mg

待询

2-4周

生物活性

产品描述	Anti-Mouse CTLA-4/CD152 (LALA-PG) Antibody (9D9) is a mouse-derived inhibitory antibody targeting mouse CTLA-4/CD152. The Fc fragment carries the LALA-PG mutation, which abolishes binding to endogenous Fcγ receptors. It has been applied in cancer and immunology-related research, such as colon cancer.
体内活性	Anti-Mouse CTLA-4/CD152 (LALA-PG) Antibody (9D9) 采用腹腔注射方式给药，注射前1天给予500 μg剂量，第2天和第5天各给予250 μg剂量时，可显著增加NP2W1S-GFP移植小鼠体内的调节性T细胞、T滤泡辅助细胞及T滤泡调节细胞数量[1]； Anti-Mouse CTLA-4/CD152 (LALA-PG) Antibody (9D9)以15 mg/kg的剂量经腹腔单次注射时，在colon 26结肠肿瘤模型小鼠中表现出显著的抗肿瘤活性[2]。
别名	9D9
克隆号	9D9
反应种属	Mouse
应用	ELISA FACS Functional assay
抗体种类	Monoclonal
缓冲液	Supplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition.
内毒素	<1.0 EU/mg

偶联与修饰

偶联	Unconjugated

抗原信息

靶点	CTLA-4/CD152(LALA-PG)

储存&溶解度

存储	Store at -20°C Shipping with blue ice/Shipping at ambient temperature. 实际储存温度请以COA为准

Anti-Mouse CTLA-4/CD152 (LALA-PG) Antibody (9D9)