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Anti-EGFR Antibody-PE (5D853)
还可以产品编号 TMAY-00022P
Anti-EGFR Antibody-PE (5D853) 是一种 PE-conjugated Mouse 抗体，靶向 EGFR。Anti-EGFR Antibody-PE (5D853) 可用于 FCM。
Anti-EGFR Antibody-PE (5D853)
Anti-EGFR Antibody-PE (5D853)
还可以产品编号 TMAY-00022P
Anti-EGFR Antibody-PE (5D853) 是一种 PE-conjugated Mouse 抗体，靶向 EGFR。Anti-EGFR Antibody-PE (5D853) 可用于 FCM。
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产品介绍
生物活性
偶联与修饰
抗原信息
| 产品描述 | Anti-EGFR Antibody-PE (5D853) is a PE-conjugated Mouse antibody targeting EGFR. Anti-EGFR Antibody-PE (5D853) can be used in FCM. |
| Ig Type | Monoclonal Mouse IgG1 |
| 克隆号 | 5D853 |
| 交叉反应 | Human |
| 验证活性 | Flow cytometric analysis of EGFR expression on human A431 cells. |
| 应用 | FCM |
| 推荐剂量 | 2 μl/Test, 0.1 mg/ml |
| 抗体种类 | Monoclonal |
| 宿主来源 | Mouse |
| 构建方式 | This product is a recombinant monoclonal antibody expressed from HEK293 cells. Then conjugated with PE under optimum conditions, the unreacted PE was removed. |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | PBS solution containing 0.5% BSA and 0.03%ProClin300 |
| 研究背景 | As a member of the epidermal growth factor receptor (EGFR) family, EGFR protein is type I transmembrane glycoprotein that binds a subset of EGF family ligands including EGF, amphiregulin, TGF-α, betacellulin, etc. EGFR protein plays a crucial role in signaling pathway in the regulation of cell proliferation, survival and differentiation. Binding of a ligand induces EGFR protein homo- or heterodimerization, the subsequent tyrosine autophosphorylation and initiates various down stream pathways (MAPK, PI3K/PKB and STAT). In addition, EGFR signaling also has been shown to exert action on carcinogenesis and disease progression, and thus EGFR protein is proposed as a target for cancer therapy currently.Cancer ImmunotherapyImmune CheckpointImmunotherapyTargeted Therapy |
| 偶联 | PE |
| 其他可选修饰符 | Unconjugated/APC/FITC/Biotin |
| 可提供抗体种类 | 5 |
| 免疫原 | Recombinant Human EGFR / HER1 / ErbB1 protein (TMPY-00742) |
| 抗原种属 | Human |
| 研究领域 | Cancer Drug Targets, Receptor Tyrosine Kinases (RTKs) |
存储&运输
| 储存方式 | Store at 2°C-8°C for 12 months, do not freeze. Keep away from direct sunlight. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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