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Interleukin-33 (IL-33) is a cytokine belonging to the IL-1 family, playing a role in inflammatory, infectious and autoimmune diseases and expressed in the cellular nucleus in several tissues. High levels of IL-33 are expressed in epithelial barrier tissues and endothelial barriers. ST2 is a receptor for IL-33, expressed selectively on a subset of Th2 cells, mediating some of their functions.

| 规格 | 价格 | 库存 | 数量 | 
|---|---|---|---|
| 5 μg | ¥ 388  | 6-8日内发货 | |
| 10 μg | ¥ 625  | 6-8日内发货 | |
| 20 μg | ¥ 987  | 5日内发货 | |
| 50 μg | ¥ 1,980  | 5日内发货 | |
| 100 μg | ¥ 3,400  | 5日内发货 | |
| 200 μg | ¥ 6,160  | 5日内发货 | |
| 500 μg | ¥ 13,600  | 5日内发货 | 
| 生物活性 | Human IL-1RL1, His Tag immobilized on CM5 Chip can bind Cynomolgus IL-33, His Tag with an affinity constant of 46.85 nM as determined in SPR assay.  | 
| 产品描述 | Interleukin-33 (IL-33) is a cytokine belonging to the IL-1 family, playing a role in inflammatory, infectious and autoimmune diseases and expressed in the cellular nucleus in several tissues. High levels of IL-33 are expressed in epithelial barrier tissues and endothelial barriers. ST2 is a receptor for IL-33, expressed selectively on a subset of Th2 cells, mediating some of their functions.  | 
| 种属 | Cynomolgus  | 
| 表达系统 | HEK293 Cells  | 
| 标签 | N-His | 
| 蛋白编号 | A0A2K5W3I1-1 | 
| 别名 | RP11-575C20.2,NF-HEV,NFEHEV,IL33,IL1F11,DVS27,DV27,C9orf26 Z,C9ORF26  | 
| 蛋白构建 | His109-Ile270  | 
| 蛋白纯度 | > 95% as determined by Tris-Bis PAGE  | 
| 分子量 | 19.2 kDa (predicted). Due to glycosylation, the protein migrates to 25-30 kDa based on Tris-Bis PAGE result. | 
| 内毒素 | < 1 EU/μg by the LAL method. | 
| 蛋白性状 | Lyophilized powder | 
| 缓冲液 | Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS (pH 7.4). Typically, 8% trehalose is incorporated as a protective agent before lyophilization. | 
| 复溶方法 | Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.  | 
| 存储 | It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.  | 
| 运输方式 | In general, Lyophilized powders are shipping with blue ice. | 
| 研究背景 | Interleukin-33 (IL-33) is a cytokine belonging to the IL-1 family, playing a role in inflammatory, infectious and autoimmune diseases and expressed in the cellular nucleus in several tissues. High levels of IL-33 are expressed in epithelial barrier tissues and endothelial barriers. ST2 is a receptor for IL-33, expressed selectively on a subset of Th2 cells, mediating some of their functions.  |