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Anti-CYP2C9 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 CYP2C9。Anti-CYP2C9 Polyclonal Antibody 可用于 WB,IHC-P,IHC-Fr,IF。
Anti-CYP2C9 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 CYP2C9。Anti-CYP2C9 Polyclonal Antibody 可用于 WB,IHC-P,IHC-Fr,IF。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
50 μL | ¥ 1,175 | 5日内发货 | |
100 μL | ¥ 1,970 | 5日内发货 | |
200 μL | ¥ 2,790 | 5日内发货 |
产品描述 | Anti-CYP2C9 Polyclonal Antibody is a Rabbit antibody targeting CYP2C9. Anti-CYP2C9 Polyclonal Antibody can be used in WB,IHC-P,IHC-Fr,IF. |
别名 | S-mephenytoin 4-hydroxylase, Cytochrome P-450MP, Cytochrome P450 PB-1, Cytochrome P450 MP-8, Cytochrome P450 MP-4, Cytochrome P450 2C9, CYPIIC9, CYP2C9, CYP2C10, Cholesterol 25-hydroxylase, (S)-limonene 7-monooxygenase, (S)-limonene 6-monooxygenase, (R)-limonene 6-monooxygenase |
Ig Type | IgG |
交叉反应 | Mouse (predicted:Human,Rat) |
验证活性 | 1. Paraformaldehyde-fixed, paraffin embedded (Mouse liver); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 min; Blocking buffer (normal goat serum) at 37°C for 30 min; Antibody incubation with (CYP2C9) Polyclonal Antibody, Unconjugated (TMAB-00524) at 1:400 overnight at 4°C, followed by a conjugated secondary antibody for 20 min and DAB staining. 2. Sample: Lane 1: Mouse Liver tissue lysates Lane 2: Mouse Stomach tissue lysates Primary: Anti-CYP2C9 (TMAB-00524) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 56 kDa Observed band size: 52 kDa |
应用 | |
推荐剂量 | WB: 1:500-2000; IHC-P: 1:200-800; IHC-Fr: 1:50-200; IF: 1:50-200 |
抗体种类 | Polyclonal |
宿主来源 | Rabbit |
亚细胞定位 | Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein. |
构建方式 | Hybridoma Polyclonal Antibody |
纯化方式 | Protein A purified |
性状 | Liquid |
缓冲液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
研究背景 | This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by rifampin. The enzyme is known to metabolize many xenobiotics, including phenytoin, tolbutamide, ibuprofen and S-warfarin. Studies identifying individuals who are poor metabolizers of phenytoin and tolbutamide suggest that this gene is polymorphic. The gene is located within a cluster of cytochrome P450 genes on chromosome 10q24. [provided by RefSeq, Jul 2008] |
免疫原 | KLH conjugated synthetic peptide: human CYP2C9 |
抗原种属 | Human |
基因ID | |
Uniprot ID | |
研究领域 | Cytochromes,Drug metabolism,Lipases,Cytochromes,Drug metabolism,Lipid metabolism |
储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
运输方式 | Shipping with blue ice. |
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