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Anti-CYP2C9 Polyclonal Antibody

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Anti-CYP2C9 Polyclonal Antibody
产品编号 TMAB-00524
别名 S-mephenytoin 4-hydroxylase, Cytochrome P-450MP, Cytochrome P450 PB-1, Cytochrome P450 MP-8, Cytochrome P450 MP-4, Cytochrome P450 2C9, CYPIIC9, CYP2C9, CYP2C10, Cholesterol 25-hydroxylase, (S)-limonene 7-monooxygenase, (S)-limonene 6-monooxygenase, (R)-limonene 6-monooxygenase

Anti-CYP2C9 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 CYP2C9。Anti-CYP2C9 Polyclonal Antibody 可用于 WB,IHC-P,IHC-Fr,IF。

Anti-CYP2C9 Polyclonal Antibody

Anti-CYP2C9 Polyclonal Antibody

Rating icon 还可以
Anti-CYP2C9 Polyclonal Antibody
产品编号 TMAB-00524 别名 S-mephenytoin 4-hydroxylase, Cytochrome P-450MP, Cytochrome P450 PB-1, Cytochrome P450 MP-8, Cytochrome P450 MP-4, Cytochrome P450 2C9, CYPIIC9, CYP2C9, CYP2C10, Cholesterol 25-hydroxylase, (S)-limonene 7-monooxygenase, (S)-limonene 6-monooxygenase, (R)-limonene 6-monooxygenase

Anti-CYP2C9 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 CYP2C9。Anti-CYP2C9 Polyclonal Antibody 可用于 WB,IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,175
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100 μL
¥ 1,970
5日内发货
200 μL
¥ 2,790
5日内发货
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产品介绍

生物活性
产品描述
Anti-CYP2C9 Polyclonal Antibody is a Rabbit antibody targeting CYP2C9. Anti-CYP2C9 Polyclonal Antibody can be used in WB,IHC-P,IHC-Fr,IF.
别名S-mephenytoin 4-hydroxylase, Cytochrome P-450MP, Cytochrome P450 PB-1, Cytochrome P450 MP-8, Cytochrome P450 MP-4, Cytochrome P450 2C9, CYPIIC9, CYP2C9, CYP2C10, Cholesterol 25-hydroxylase, (S)-limonene 7-monooxygenase, (S)-limonene 6-monooxygenase, (R)-limonene 6-monooxygenase
Ig Type
IgG
交叉反应
Mouse (predicted:Human,Rat)
验证活性
1. Paraformaldehyde-fixed, paraffin embedded (Mouse liver); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 min; Blocking buffer (normal goat serum) at 37°C for 30 min; Antibody incubation with (CYP2C9) Polyclonal Antibody, Unconjugated (TMAB-00524) at 1:400 overnight at 4°C, followed by a conjugated secondary antibody for 20 min and DAB staining.
2. Sample:
Lane 1: Mouse Liver tissue lysates
Lane 2: Mouse Stomach tissue lysates
Primary: Anti-CYP2C9 (TMAB-00524) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 56 kDa
Observed band size: 52 kDa
应用
推荐剂量
WB: 1:500-2000; IHC-P: 1:200-800; IHC-Fr: 1:50-200; IF: 1:50-200
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
研究背景This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by rifampin. The enzyme is known to metabolize many xenobiotics, including phenytoin, tolbutamide, ibuprofen and S-warfarin. Studies identifying individuals who are poor metabolizers of phenytoin and tolbutamide suggest that this gene is polymorphic. The gene is located within a cluster of cytochrome P450 genes on chromosome 10q24. [provided by RefSeq, Jul 2008]
抗原信息
免疫原
KLH conjugated synthetic peptide: human CYP2C9
抗原种属
Human
基因ID
Uniprot ID
研究领域
Cytochromes,Drug metabolism,Lipases,Cytochromes,Drug metabolism,Lipid metabolism
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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