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Anti-Rack1 Antibody (8C519)
还可以产品编号 TMAC-03499
别名 RACK1, PIG21, HLC-7, H12.3, Gnb2-rs1
Anti-Rack1 Antibody (8C519) 是一种 Rabbit 抗体，靶向 Rack1。Anti-Rack1 Antibody (8C519) 可用于 FCM,IHC,WB。
Anti-Rack1 Antibody (8C519)
Anti-Rack1 Antibody (8C519)
一键复制产品信息 还可以产品编号 TMAC-03499 别名 RACK1, PIG21, HLC-7, H12.3, Gnb2-rs1
Anti-Rack1 Antibody (8C519) 是一种 Rabbit 抗体，靶向 Rack1。Anti-Rack1 Antibody (8C519) 可用于 FCM,IHC,WB。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,480 | 5日内发货 | |
| 100 μL | ¥ 2,480 | 5日内发货 |
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产品介绍
生物活性
偶联与修饰
抗原信息
化学信息
| 产品描述 | Anti-Rack1 Antibody (8C519) is a Rabbit antibody targeting Rack1. Anti-Rack1 Antibody (8C519) can be used in FCM,IHC,WB. |
| 别名 | RACK1, PIG21, HLC-7, H12.3, Gnb2-rs1 |
| Ig Type | IgG |
| 克隆号 | 8C519 |
| 交叉反应 | Human,Mouse,Rat |
| 验证活性 | 1. Western blot analysis of RACK1 on different lysates using anti-RACK1 antibody at 1/2,000 dilution. Positive control: Lane 1: SH-SY-5Y, Lane 2: Rat small intestine. 2. Immunohistochemical analysis of paraffin-embedded rat cerebellum tissue using anti-RACK1 antibody. Counter stained with hematoxylin. 3. Immunohistochemical analysis of paraffin-embedded rat liver tissue using anti-RACK1 antibody. Counter stained with hematoxylin. 4. Immunohistochemical analysis of paraffin-embedded human colon tissue using anti-RACK1 antibody. Counter stained with hematoxylin. 5. Immunohistochemical analysis of paraffin-embedded mouse skin tissue using anti-RACK1 antibody. Counter stained with hematoxylin. 6. Flow cytometric analysis of SH-SY-5Y cells with RACK1 antibody at 1/100 dilution (purple) compared with an unlabelled control (cells without incubation with primary antibody; yellow). Alexa Fluor 488-conjugated goat anti-rabbit IgG was used as the secondary antibody.       |
| 应用 | FCMIHCWB |
| 推荐剂量 | WB: 1:1000-2000; IHC: 1:50-200; FCM: 1:50-100 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 构建方式 | Recombinant Antibody |
| 纯化方式 | ProA affinity purified |
| 性状 | Liquid |
| 缓冲液 | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| 研究背景 | Members of the protein kinase C (PKC) family play a key regulatory role in a variety of cellular functions, including cell growth and differentiation, gene expression, hormone secretion and membrane function. Receptor for activated C kinases, termed RACKs, are intracellular receptors for activated PKC that may be involved in the activation-induced translocation of PKC. RACK1 (receptor for activated C kinase 1) is a 317 amino acid G protein b subunit-like protein that functions as a RACK and inhibits the activity of Src tyrosine kinases. In response to PKC activation, the intracellular localization of RACK1 and PKC bII changes, and RACK1 and PKC bII co-localize to the same sites. RACK1 is therefore thought to be a shuttling protein for PKC bII. A deficit in RACK1 may be associated with impaired PKC activation in the aging brain. The RACK1 gene is conserved in chimpanzee, dog, cow, mouse, rat, chicken, zebrafish, fruit fly, mosquito, C.elegans, S.pombe, S.cerevisiae, K.lactis, E.gossypii, M.grisea, N.crassa, A.thaliana, rice and P.falciparum, and maps to human chromosome 5q35.3. |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Protein: C-terminal human RACK1 |
| 抗原种属 | human |
| Uniprot ID |
| 分子量 | Theoretical: 35 kDa. |
存储&运输
| 储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
计算器
比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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