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Anti-ADGRE1 Polyclonal Antibody 2

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货号 TMAB-00061

别名 TM7LN3, Lymphocyte antigen 71, Ly71, Gpf480, F4/80, EMR1 hormone receptor, EMR1, EMR 1, EGFTM7, EGF-like module-containing mucin-like hormone receptor-like 1, EGF-like module receptor 1, EGF TM7, EGF like module receptor 1, Egf like module containing mucin like hormone receptor like sequence 1, Egf like module containing mucin like hormone receptor like 1, DD7A5 7, Cell surface glycoprotein F4/80, Cell surface glycoprotein EMR1, AGRE1, Adhesion G protein-coupled receptor E1

Anti-ADGRE1 Polyclonal Antibody 2 是一种 Rabbit 抗体，靶向 ADGRE1。Anti-ADGRE1 Polyclonal Antibody 2 可用于 IF,IHC-Fr,IHC-P。

Anti-ADGRE1 Polyclonal Antibody 2

Anti-ADGRE1 Polyclonal Antibody 2

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货号 TMAB-00061 别名 TM7LN3, Lymphocyte antigen 71, Ly71, Gpf480, F4/80, EMR1 hormone receptor, EMR1, EMR 1, EGFTM7, EGF-like module-containing mucin-like hormone receptor-like 1, EGF-like module receptor 1, EGF TM7, EGF like module receptor 1, Egf like module containing mucin like hormone receptor like sequence 1, Egf like module containing mucin like hormone receptor like 1, DD7A5 7, Cell surface glycoprotein F4/80, Cell surface glycoprotein EMR1, AGRE1, Adhesion G protein-coupled receptor E1

Anti-ADGRE1 Polyclonal Antibody 2 是一种 Rabbit 抗体，靶向 ADGRE1。Anti-ADGRE1 Polyclonal Antibody 2 可用于 IF,IHC-Fr,IHC-P。

规格价格库存数量
50 μL
¥ 1,170
5日内发货
100 μL
¥ 1,975
5日内发货
200 μL
¥ 2,780
5日内发货
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产品介绍

生物活性
产品描述
Anti-ADGRE1 Polyclonal Antibody 2 is a Rabbit antibody targeting ADGRE1. Anti-ADGRE1 Polyclonal Antibody 2 can be used in IF,IHC-Fr,IHC-P.
别名TM7LN3, Lymphocyte antigen 71, Ly71, Gpf480, F4/80, EMR1 hormone receptor, EMR1, EMR 1, EGFTM7, EGF-like module-containing mucin-like hormone receptor-like 1, EGF-like module receptor 1, EGF TM7, EGF like module receptor 1, Egf like module containing mucin like hormone receptor like sequence 1, Egf like module containing mucin like hormone receptor like 1, DD7A5 7, Cell surface glycoprotein F4/80, Cell surface glycoprotein EMR1, AGRE1, Adhesion G protein-coupled receptor E1
Ig Type
IgG
反应种属
Mouse
验证活性
1. Paraformaldehyde-fixed, paraffin embedded Mouse Liver; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Antibody incubation with ADGRE1 Polyclonal Antibody, Unconjugated (TMAB-00061) at 1:400 overnight at 4°C, followed by conjugation to the SP Kit (Rabbit) and DAB staining.
2. Paraformaldehyde-fixed, paraffin embedded Mouse Cerebrum; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Antibody incubation with ADGRE1 Polyclonal Antibody, Unconjugated (TMAB-00061) at 1:400 overnight at 4°C, followed by conjugation to the SP Kit (Rabbit) and DAB staining.
3. Paraformaldehyde-fixed, paraffin embedded Mouse Spleen; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Antibody incubation with ADGRE1 Polyclonal Antibody, Unconjugated (TMAB-00061) at 1:400 overnight at 4°C, followed by conjugation to the SP Kit (Rabbit) and DAB staining.
4. Paraformaldehyde-fixed, paraffin embedded Mouse Small Intestine; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Antibody incubation with ADGRE1 Polyclonal Antibody, Unconjugated (TMAB-00061) at 1:400 overnight at 4°C, followed by conjugation to the SP Kit (Rabbit) and DAB staining.
verifiedActivityverifiedActivityverifiedActivityverifiedActivity
应用IFIHC-FrIHC-P
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Cell membrane.
组织特异性Wide expression; increased levels in peripheral blood mononuclear cells.
构建方式Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1 mg/mL
研究背景The epidermal growth factor (EGF)-TM7 family constitutes a group of class B G-protein coupled receptors, which includes CD97, EMR1 (EGF-like molecule containing mucin-like hormone receptor 1, designated F4/80 in mouse), EMR2, EMR3, FIRE, and ETL (1–3). These family members are characterized by an extended extracellular region with several N-terminal EGF domains, and are predominantly expressed on cells of the immune system (1–3). The EGF-TM7 protein family are encoded by a gene cluster on human chromosome 19p13 (1,3,4). The F4/80 molecule is solely expressed on the surface of macrophages and serves as a marker for mature macrophage tissues, including Kupffer cells in liver, splenic red pulp macrophages, brain microglia, gut lamina propria, and Langerhans cells in the skin (1). F4/80/EMR1 undergoes extensive N-linked glycosylation as well as some O-linked glycosylation (5,6). The function of F4/80/EMR1 is unclear, but it is speculated to be involved in macrophage adhesion events, cell migration, or as a G-protein coupled signaling component of macrophages.
抗原信息
免疫原
KLH conjugated synthetic peptide: human ADGRE1
抗原种属
Human
基因名称
ADGRE1
基因ID
2015
蛋白名称
Adhesion G protein-coupled receptor E1
Uniprot ID
Q14246
研究领域
Macrophage / Inflamm.,Other Cell Types
功能
Could be involved in cell-cell interactions.
化学信息
分子量Theoretical: 95 kDa.
储存&溶解度
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | store at -20°C

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