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Anti-LRRTM1 Polyclonal Antibody

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货号 TMAB-08426

Anti-LRRTM1 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 LRRTM1。Anti-LRRTM1 Polyclonal Antibody 可用于 WB。

Anti-LRRTM1 Polyclonal Antibody

Anti-LRRTM1 Polyclonal Antibody

一键复制产品信息
Rating icon 还可以
货号 TMAB-08426

Anti-LRRTM1 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 LRRTM1。Anti-LRRTM1 Polyclonal Antibody 可用于 WB。

规格价格库存数量
50 μL
¥ 1,160
5日内发货
100 μL
¥ 1,965
5日内发货
200 μL
¥ 2,780
5日内发货
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产品介绍


生物活性
产品描述
Anti-LRRTM1 Polyclonal Antibody is a Rabbit antibody targeting LRRTM1. Anti-LRRTM1 Polyclonal Antibody can be used in WB.
Ig Type
IgG
反应种属
Human (predicted:Mouse,Rat,Chicken,Dog,Pig,Cow)
应用WB
推荐剂量
WB: 1:500-2000
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Cell membrane; Single-pass type I membrane protein (By similarity). Cell junction, synapse, postsynaptic cell membrane; Single-pass type I membrane protein (By similarity).
组织特异性Predominantly expression in forebrain regions including thalamus and cerebral cortex.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景The leucine-rich (LRR) repeat is a 20-30 amino acid motif that forms a hydrophobic Alpha/Beta horseshoe fold, allowing it to accommodate several leucine residues within a tightly packed core. All LRR repeats contain a variable segment and a highly conserved segment, the latter of which accounts for 11 or 12 residues of the entire LRR motif. LRRTM1 (leucine rich repeat transmembrane neuronal 1) is a 522 amino acid single-pass type I membrane protein that localizes to the endoplasmic reticulum and contains ten LRR repeats. Expressed predominately in forebrain tissue, LRRTM1 is thought to be involved in the development of forebrain structures, specifically by influencing axon trafficking, as well as neuronal differentiation and connectivity. Human LRRTM1 shares 96% amino acid identity with its mouse counterpart, suggesting a conserved role between species. Defects in the gene encoding LRRTM1 may be associated with the pathogenesis of several common neurodevelopmental disorders.
抗原信息
免疫原
KLH conjugated synthetic peptide: human LRRTM1
抗原种属
Human
基因名称
LRRTM1
基因ID
蛋白名称
Leucine-rich repeat transmembrane neuronal protein 1
Uniprot ID
功能
May play a role during the development of specific forebrain structures by influencing neuronal differentiation and connectivity, with a possible role in intracellular trafficking within axons.
化学信息
分子量Theoretical: 55 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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