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Anti-NKX2.2 Antibody (1F181)

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产品编号 TMAC-02851
别名 tinman, Nkx2b, NKX22_HUMAN, NKX2-2, NKX22, NKX2 2, NK2 transcription factor related locus 2, NK2 transcription factor like protein B, NK2 homeobox 2, NK 2 homolog B, Homeobox protein Nkx-2.2, Homeobox protein Nkx 2.2, Homeobox protein NK-2 homolog B, Homeobox protein NK 2 homolog B

Anti-NKX2.2 Antibody (1F181) 是一种 Mouse 抗体，靶向 NKX2.2。Anti-NKX2.2 Antibody (1F181) 可用于 FCM,WB。

Anti-NKX2.2 Antibody (1F181)

Anti-NKX2.2 Antibody (1F181)

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产品编号 TMAC-02851 别名 tinman, Nkx2b, NKX22_HUMAN, NKX2-2, NKX22, NKX2 2, NK2 transcription factor related locus 2, NK2 transcription factor like protein B, NK2 homeobox 2, NK 2 homolog B, Homeobox protein Nkx-2.2, Homeobox protein Nkx 2.2, Homeobox protein NK-2 homolog B, Homeobox protein NK 2 homolog B

Anti-NKX2.2 Antibody (1F181) 是一种 Mouse 抗体，靶向 NKX2.2。Anti-NKX2.2 Antibody (1F181) 可用于 FCM,WB。

规格价格库存数量
50 μL
¥ 1,980
5日内发货
100 μL
¥ 2,985
5日内发货
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产品介绍

生物活性
产品描述
Anti-NKX2.2 Antibody (1F181) is a Mouse antibody targeting NKX2.2. Anti-NKX2.2 Antibody (1F181) can be used in FCM,WB.
别名tinman, Nkx2b, NKX22_HUMAN, NKX2-2, NKX22, NKX2 2, NK2 transcription factor related locus 2, NK2 transcription factor like protein B, NK2 homeobox 2, NK 2 homolog B, Homeobox protein Nkx-2.2, Homeobox protein Nkx 2.2, Homeobox protein NK-2 homolog B, Homeobox protein NK 2 homolog B
克隆号
1F181
交叉反应
Human
验证活性
1. Western blot analysis of NKX2.2 on human NKX2.2 recombinant protein using anti-NKX2.2 antibody at 1/1,000 dilution.
2. Flow cytometric analysis of MCF-7 cells with NKX2.2 antibody at 1/100 dilution (green) compared with an unlabelled control (cells without incubation with primary antibody; red).
verifiedActivityverifiedActivity
应用FCMWB
推荐剂量
WB: 1:500-1000; FCM: 1:100-200
抗体种类
Monoclonal
宿主来源Mouse
构建方式Hybridoma Monoclonal Antibody
纯化方式ProA affinity purified
性状Liquid
缓冲液1*TBS (pH7.4), 1%BSA, Preservative: 0.05% Sodium Azide.
研究背景Members of the NK-2 family of homeodomain proteins are key regulators of growth and development in several tissues, including brain, heart and pancreas. During neural development, sonic hedgehog (Shh) is known to control cell fate and mitogenesis, which is correlated with Shh dose-dependent expression of several genes, including Nkx-2.1, Nkx-2.2 and Nkx-2.9. Specifically, the Nkx-2.2 protein is responsible for directing ventral neuronal patterning in response to graded Shh signaling. In the pancreas, Nkx-2.2 is expressed in a, b and pancreatic polypeptide (PP) cells, but not in d cells. Nkx-2.2 expression is required for differentiation of pancreatic b cells, which produce insulin. Homozygous null mutations of the Nkx-2.2 gene in mice lead to severe hyperglycemia and death shortly after birth, which suggests that Nkx-2.2 may be an important therapeutic target for pancreatic diseases, including diabetes and cancer.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Protein
Uniprot ID
O95096
化学信息
分子量Theoretical: 30 kDa.
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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