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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-Phospho-MAK (Tyr159) Polyclonal Antibody 2

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货号 TMAB-10926

Anti-Phospho-MAK (Tyr159) Polyclonal Antibody 2 是一种 Rabbit 抗体，靶向 Phospho-MAK (Tyr159)。Anti-Phospho-MAK (Tyr159) Polyclonal Antibody 2 可用于 WB,IHC-P,IHC-Fr,IF。

Anti-Phospho-MAK (Tyr159) Polyclonal Antibody 2

Anti-Phospho-MAK (Tyr159) Polyclonal Antibody 2

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Rating icon 还可以
货号 TMAB-10926

Anti-Phospho-MAK (Tyr159) Polyclonal Antibody 2 是一种 Rabbit 抗体，靶向 Phospho-MAK (Tyr159)。Anti-Phospho-MAK (Tyr159) Polyclonal Antibody 2 可用于 WB,IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,175
5日内发货
100 μL
¥ 1,965
5日内发货
200 μL
¥ 2,795
5日内发货
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产品介绍

生物活性
产品描述
Anti-Phospho-MAK (Tyr159) Polyclonal Antibody 2 is a Rabbit antibody targeting Phospho-MAK (Tyr159). Anti-Phospho-MAK (Tyr159) Polyclonal Antibody 2 can be used in WB,IHC-P,IHC-Fr,IF.
Ig Type
IgG
反应种属
Human,Mouse,Rat
应用WBIHC-PIHC-FrIF
推荐剂量
WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Nucleus. Cytoplasm > cytoskeleton > centrosome. Cytoplasm > cytoskeleton > spindle. Midbody. Cell projection > cilium > photoreceptor outer segment. Photoreceptor inner segment. Localized in both the connecting cilia and the outer segment axonemes (By similarity). Localized uniformly in nuclei during interphase, to the mitotic spindle and centrosomes during metaphase and anaphase, and also to midbody at anaphase until telophase.
组织特异性Expressed in prostate cancer cell lines at generally higher levels than in normal prostate epithelial cell lines. Isoform 1 is expressed in kidney, testis, lung, trachea, and retina. Isoform 2 is retina-specific where it is expressed in rod and cone photoreceptors.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景The product of this gene is a serine/threonine protein kinase related to kinases involved in cell cycle regulation. It is expressed almost exclusively in the testis, primarily in germ cells. Studies of the mouse and rat homologs have localized the kinase to the chromosomes during meiosis in spermatogenesis, specifically to the synaptonemal complex that exists while homologous chromosomes are paired. There is, however, a study of the mouse homolog that has identified high levels of expression in developing sensory epithelia so its function may be more generalized. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2011]
抗原信息
免疫原
KLH conjugated synthesised phosphopeptide: human MAK around the phosphorylation site of Tyr159
抗原种属
Human
基因名称
Mak
基因ID
4117
蛋白名称
Serine/threonine-protein kinase MAK
Uniprot ID
P20794
功能
Essential for the regulation of ciliary length and required for the long-term survival of photoreceptors (By similarity). Phosphorylates FZR1 in a cell cycle-dependent manner. Plays a role in the transcriptional coactivation of AR. Could play an important function in spermatogenesis. May play a role in chromosomal stability in prostate cancer cells.
化学信息
分子量Theoretical: 71 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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