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Anti-Thioredoxin/TRX Antibody (2M628)

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Anti-Thioredoxin/TRX Antibody (2M628)
产品编号 TMAC-04030
别名 TXN, TRX1, TRX, TRDX, Thioredoxin, Surface-Associated Sulphydryl Protein, SASP, ATL-Derived Factor, ADF

Anti-Thioredoxin/TRX Antibody (2M628) 是一种 Rabbit 抗体,靶向 Thioredoxin/TRX。Anti-Thioredoxin/TRX Antibody (2M628) 可用于 WB,FCM。

Anti-Thioredoxin/TRX Antibody (2M628)

Anti-Thioredoxin/TRX Antibody (2M628)

Rating icon 还可以
Anti-Thioredoxin/TRX Antibody (2M628)
产品编号 TMAC-04030 别名 TXN, TRX1, TRX, TRDX, Thioredoxin, Surface-Associated Sulphydryl Protein, SASP, ATL-Derived Factor, ADF

Anti-Thioredoxin/TRX Antibody (2M628) 是一种 Rabbit 抗体,靶向 Thioredoxin/TRX。Anti-Thioredoxin/TRX Antibody (2M628) 可用于 WB,FCM。

规格价格库存数量
50 μL
¥ 1,490
5日内发货
100 μL
¥ 2,495
5日内发货
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产品介绍

生物活性
产品描述
Anti-Thioredoxin/TRX Antibody (2M628) is a Rabbit antibody targeting Thioredoxin/TRX. Anti-Thioredoxin/TRX Antibody (2M628) can be used in WB,FCM.
别名TXN, TRX1, TRX, TRDX, Thioredoxin, Surface-Associated Sulphydryl Protein, SASP, ATL-Derived Factor, ADF
Ig Type
IgG
交叉反应
Human,Mouse,Rat
验证活性
1. Western blot analysis of TRX1 on different lysates using anti-TRX1 antibody at 1/1,000 dilution. Positive control: Lane 1: Hela, Lane 2: 293T.
2. Flow cytometric analysis of Hela cells with TRX1 antibody at 1/50 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black). Alexa Fluor 488-conjugated goat anti rabbit IgG was used as the secondary antibody.
应用
推荐剂量
WB: 1:1000-5000; FCM: 1:50-100
抗体种类
Monoclonal
宿主来源Rabbit
构建方式Recombinant Antibody
纯化方式ProA affinity purified
性状Liquid
缓冲液1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
研究背景Thioredoxin (Trx) is a redox protein that is found in several species, such as bacteria, plants and mammals, and contains a conserved active site, consisting of Trp-Cys-Gly-Pro-Cys. Trx has several biological functions. It acts as a hydrogen donor for ribonucleotide reductase, which is critical for DNA synthesis, and modulates the DNA-binding activity of several transcription factors, including NFkB, AP-1, p53, TFIIIC and glucocorticoid receptor. Trx also stimulates cell growth, is an inhibitor of apoptosis and plays a role in the protection against oxidative stress. Drugs that inhibit Trx have antitumor activity, suggesting that Trx is involved in a variety of human diseases, including cancer. TrxR is a ubiquitously expressed flavoprotein that catalyzes the NADPH-dependent reduction of Trx as well as several other oxidized cellular components.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Protein
Uniprot ID
化学信息
分子量Theoretical: 12 kDa.
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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