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Anti-IL-1R2 Antibody-HRP (2D422)
还可以产品编号 TMAY-00280H
Anti-IL-1R2 Antibody-HRP (2D422) 是一种 HRP-conjugated Mouse 抗体，靶向 IL-1R2。Anti-IL-1R2 Antibody-HRP (2D422) 可用于 ELISA。
Anti-IL-1R2 Antibody-HRP (2D422)
Anti-IL-1R2 Antibody-HRP (2D422)
还可以产品编号 TMAY-00280H
Anti-IL-1R2 Antibody-HRP (2D422) 是一种 HRP-conjugated Mouse 抗体，靶向 IL-1R2。Anti-IL-1R2 Antibody-HRP (2D422) 可用于 ELISA。
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| 产品描述 | Anti-IL-1R2 Antibody-HRP (2D422) is a HRP-conjugated Mouse antibody targeting IL-1R2. Anti-IL-1R2 Antibody-HRP (2D422) can be used in ELISA. |
| Ig Type | Monoclonal Mouse IgG1 |
| 克隆号 | 2D422 |
| 交叉反应 | Human |
| 应用 | ELISA |
| 推荐剂量 | ELISA: 0.1-1 μg/ml |
| 抗体种类 | Monoclonal |
| 宿主来源 | Mouse |
| 构建方式 | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human IL-1R2 / CD121b (rh IL-1R2 / CD121b; TMPY-01366; NP_004624.1; Met1-Glu343). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography and conjugated with horseradish-peroxidase (HRP). |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | 0.2 μm filtered solution in PBS |
| 研究背景 | Interleukin 1 receptor, type II (IL1R2) also known as CD121b (Cluster of Differentiation 121b) is a cytokine receptor that belongs to the interleukin-1 receptor family. This protein binds interleukin alpha (IL1A), interleukin beta (IL1B), and interleukin 1 receptor, type I (IL1R1/IL1RA), and acts as a decoy receptor that inhibits the activity of its ligands. The pleiotropic cytokine IL1 is produced to regulate the development and maintenance of the inflammatory responses and binds to specific plasma membrane receptors on cells. Two distinct types of IL1 receptors that can bind IL1 specifically have been identified, designated as IL1RI (IL1RA) and IL1RII (IL1RB). IL1R1 contributes to IL-1 signaling, whereas the IL-1R2/CD121b has no signaling property and acts as a decoy for IL-1. IL-1R2/CD121b structurally consisting of a ligand-binding portion comprised of three Ig-like domains, a single transmembrane region, and a short cytoplasmic domain is expressed in a variety of cell types including B lymphocytes, neutrophils, monocytes, large granular leukocytes, and endothelial cells. Interleukin 4 (IL4) is reported to antagonize the activity of interleukin 1 by inducing the expression and release of this cytokine. |
| 偶联 | HRP |
| 其他可选修饰符 | Unconjugated |
| 可提供抗体种类 | 2 |
| 免疫原 | Recombinant Human IL-1R2 / CD121b Protein (TMPY-01366) |
| 抗原种属 | Human |
| 研究领域 | Neuroinflammation |
存储&运输
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. Keep away from direct sunlight. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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