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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-Claudin 19 Polyclonal Antibody

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货号 TMAB-04423

Anti-Claudin 19 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Claudin 19。Anti-Claudin 19 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

Anti-Claudin 19 Polyclonal Antibody

Anti-Claudin 19 Polyclonal Antibody

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Rating icon 还可以
货号 TMAB-04423

Anti-Claudin 19 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Claudin 19。Anti-Claudin 19 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,170
5日内发货
100 μL
¥ 1,975
5日内发货
200 μL
¥ 2,780
5日内发货
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产品介绍

生物活性
产品描述
Anti-Claudin 19 Polyclonal Antibody is a Rabbit antibody targeting Claudin 19. Anti-Claudin 19 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
反应种属
Mouse (predicted:Human,Rat,Cow,Horse,Sheep)
应用IHC-PIHC-FrIF
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Cell junction, tight junction. Cell membrane; Multi-pass membrane protein.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景The Claudin superfamily consists of many structurally related proteins in humans. These proteins are important structural and functional components of tight junctions in paracellular transport. Claudins are located in both epithelial and endothelial cells in all tight junction-bearing tissues. Three classes of proteins are known to localize to tight junctions, including the claudins, Occludin and Junction adhesion molecules. Claudins, which consist of four transmembrane domains and two extracellular loops, make up tight junction strands. Claudin expression is often highly restricted to specfic regions of different tissues and may have an important role in transcellular transport through tight junctions. Claudin-19 is a 224 amino acid multi-pass membrane protein that belongs to the claudin family and is expressed as two isoforms due to alternative splicing events. Defects in the gene encoding claudin-19 are the cause of hypomagnesemia renal with ocular involvement (HOMGO), a renal disease characterized by hypomagnesemia, hypercalciuria and nephrocalcinosis.
抗原信息
免疫原
KLH conjugated synthetic peptide: human Claudin 19
抗原种属
Human
基因名称
CLDN19
基因ID
149461
蛋白名称
Claudin-19
Uniprot ID
Q8N6F1
功能
CLDN19 belongs to the claudin family. It plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
化学信息
分子量Theoretical: 23 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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