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别名 抗F3/Factor III/Tissue Factor/CD142 抗体
Anti-F3/Factor III/Tissue Factor/CD142 Antibody 是一种针对人组织因子 (TF/CD142) 的高特异性单克隆抗体,通过精准识别 TF 的胞外结构域,旨在选择性阻断其介导的肿瘤信号转导或作为抗体偶联药物(ADC)的靶向载体。在实验研究中,该类抗体常被设计为不干扰 TF 与凝血因子 VIIa (FVIIa) 结合引起的正常凝血级联,从而作为在不增加出血风险的前提下抑制肿瘤增殖、阻断血管生成及评估靶向细胞毒性载荷递送效率的药理学工具。
Anti-F3/Factor III/Tissue Factor/CD142 Antibody 是一种针对人组织因子 (TF/CD142) 的高特异性单克隆抗体,通过精准识别 TF 的胞外结构域,旨在选择性阻断其介导的肿瘤信号转导或作为抗体偶联药物(ADC)的靶向载体。在实验研究中,该类抗体常被设计为不干扰 TF 与凝血因子 VIIa (FVIIa) 结合引起的正常凝血级联,从而作为在不增加出血风险的前提下抑制肿瘤增殖、阻断血管生成及评估靶向细胞毒性载荷递送效率的药理学工具。

| 产品描述 | Anti-F3/Factor III/Tissue Factor/CD142 Antibody represents a highly specialized monoclonal antibody specifically engineered to target the human Tissue Factor (TF/CD142) with exceptional binding affinity. It effectively facilitates the measurable targeting of TF-expressing malignant cells across various preclinical experimental models to evaluate the delivery of cytotoxic payloads or the disruption of TF-mediated oncogenic signaling during strictly monitored laboratory observation periods and functional cell viability assays without compromising systemic coagulation homeostasis. |
| 别名 | 抗F3/Factor III/Tissue Factor/CD142 抗体 |
| 反应种属 | Human |
| 应用 | ELISA FACS Functional assay |
| 抗体种类 | Monoclonal |
| 缓冲液 | Supplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition. |
| 内毒素 | <1.0 EU/mg |
| 同型 | IgG4 (S228P) |
| 推荐同型对照 |
| 偶联 | Unconjugated |
| Uniprot ID | |
| 靶点 | F3/FactorIII/TissueFactor/CD142 |
| 存储 |
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