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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-UPK3A Antibody (8Z90)

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货号 TMAB-13995

Anti-UPK3A Antibody (8Z90) 是一种 Rabbit 抗体，靶向 UPK3A。Anti-UPK3A Antibody (8Z90) 可用于 IHC-P,IHC-Fr,IF。

Anti-UPK3A Antibody (8Z90)

Anti-UPK3A Antibody (8Z90)

一键复制产品信息
Rating icon 还可以
货号 TMAB-13995

Anti-UPK3A Antibody (8Z90) 是一种 Rabbit 抗体，靶向 UPK3A。Anti-UPK3A Antibody (8Z90) 可用于 IHC-P,IHC-Fr,IF。

规格价格库存数量
25 μL
¥ 790
5日内发货
50 μL
¥ 1,385
5日内发货
100 μL
¥ 2,495
5日内发货
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产品介绍

生物活性
产品描述
Anti-UPK3A Antibody (8Z90) is a Rabbit antibody targeting UPK3A. Anti-UPK3A Antibody (8Z90) can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
克隆号
8Z90
反应种属
Human,Mouse
应用IHC-PIHC-FrIF
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Monoclonal
宿主来源Rabbit
亚细胞定位Endoplasmic reticulum membrane. Heterodimer formation with UPK1B is a prerequisite to exit out of the endoplasmic reticulum (ER).
组织特异性Expressed in ureter.
构建方式Recombinant Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景The asymmetric unit membrane (AUM) forms numerous plaques, which cover the apical surface of the urothelium. These plaques are thought to strengthen the urothelium and reduce the risk of rupturing during ladder distention. They are composed of four major integral membrane proteins called uroplakins (UP). The uroplakin family comprises UPIa, UPIb, UPII, and UPIII. Family members are conserved among several species, including human, mouse, rat, rabbit, dog, pig and sheep. UPIa and UPIb form tightly packed structures with UPII and UPIII, respectively. This pairing is required for normal urothelial plaque formation and is regulated by proteolytic processing of the uroplakin proteins. Uroplakins are expressed in normal urothelium and are used as specific markers of urothelial differentiation. They are also expressed in a majority of transitional cell carcinomas of the bladder (TCCs), which make the uroplakins a useful marker for detecting bladder cancer metastasis and for staging and monitoring chemotherapeutic response.
抗原信息
免疫原
A synthesized peptide: human Uroplakin 3a
基因名称
UPK3A
基因ID
7380
蛋白名称
Uroplakin-3a
功能
Component of the asymmetric unit membrane (AUM); a highly specialized biomembrane elaborated by terminally differentiated urothelial cells. May play an important role in AUM-cytoskeleton interaction in terminally differentiated urothelial cells. It also contributes to the formation of urothelial glycocalyx which may play an important role in preventing bacterial adherence.
化学信息
分子量Theoretical: 29 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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