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顶部产品介绍偶联与修饰抗原信息储存和溶解信息计算器

Anti-4E-BP1 Monoclonal Antibody (9P792)

Synonyms: PHAS-I, MGC4316, EIF4EBP1, BP-1, 4E-BP1, 4EBP1
货号 TMAT-0002 一键复制产品信息
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Anti-4E-BP1 Monoclonal Antibody (9P792) 是一种 Mouse 抗体，靶向 4E-BP1。Anti-4E-BP1 Monoclonal Antibody (9P792) 可用于 IHC。

Anti-4E-BP1 Monoclonal Antibody (9P792)

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Rating icon 还可以
货号 TMAT-0002

别名 PHAS-I, MGC4316, EIF4EBP1, BP-1, 4E-BP1, 4EBP1

Anti-4E-BP1 Monoclonal Antibody (9P792) 是一种 Mouse 抗体，靶向 4E-BP1。Anti-4E-BP1 Monoclonal Antibody (9P792) 可用于 IHC。

Anti-4E-BP1 Monoclonal Antibody (9P792)
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产品介绍

生物活性
产品描述
Anti-4E-BP1 Monoclonal Antibody (9P792) is a Mouse antibody targeting 4E-BP1. Anti-4E-BP1 Monoclonal Antibody (9P792) can be used in IHC.
别名
PHAS-I, MGC4316, EIF4EBP1, BP-1, 4E-BP1, 4EBP1
Ig Type
IgG1
克隆号
9P792
反应种属
Human
应用IHC
推荐剂量
IHC: 1/200-1/1000
抗体种类
Monoclonal
宿主来源Mouse
构建方式Hybridoma Monoclonal Antibody
纯化方式Purified by protein A or protein G
性状Liquid
缓冲液Ascitic fluid containing 0.03% sodium azide
浓度1 mg/ml
研究背景4E-BP1(eukaryotic translation Initiation Factor 4E Binding Protein 1),also called ELF4EBP1/BP-1/PHAS-I ,which is located on chromosome 8p12, with 118-amino acid protein (about 13kDa). Binding of eIF4EBP1 to eIF4E is reversible and is dependent on the phosphorylation status of eIF4EBP1. Non phosphorylated eIF4EBP1 will bind strongly to eIF4E while(24kDa), the phosphorylated form will not. Akt, TOR, MAP kinase, S6 kinase, and Cdc2 are known kinases capable of inactivating eIF4EBP1 binding to eIF4E by phosphorylating either threonines 35, 45, 69 or serine 64. Although, not all phosphorylation events equally block the eIF4EBP1-eIF4E interaction.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Purified recombinant fragment of 4E-BP1 expressed in E. Coli.
抗原种属
Human
基因名称
EIF4EBP1
基因ID
1978
蛋白名称
Eukaryotic translation initiation factor 4E-binding protein 1
Uniprot ID
Q13541
储存&溶解度
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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