Name: SAH
Brand: TargetMol
SKU: TQ0208
Price: 298 CNY
Availability: InStock
Rating: 5 (10 reviews)

规格

价格

库存

数量

2 mg

¥ 298

In stock

5 mg

¥ 475

In stock

10 mg

¥ 828

In stock

25 mg

¥ 1,320

In stock

50 mg

¥ 1,960

In stock

100 mg

¥ 2,930

In stock

500 mg

¥ 6,620

5日内发货

产品介绍

生物活性

产品描述	SAH (S-Adenosylhomocysteine) belongs to the group of amino acid derivatives that are intermediates in the synthesis of adenosine and cysteine. SAH is an inhibitor of the METTL3-METTL14 heterodimeric complex (IC50=0.9 µM).SAH is a regulator of several metabolic pathways.
靶点活性	METTL3-METTL14:0.9 µM, DNMT1:0.26 µM
体外活性	方法：METTL3-14 复合物用 SAH (0-100 µM) 处理，使用 METTL3-14 Assay 检测抑制活性。结果：SAH 对 METTL3-14 活性表现出强烈的抑制作用，IC50 值为 0.9±0.1 µM。[1]
别名	SAH (S-Adenosylhomocysteine), S-(5'-腺苷)-L-高半胱氨酸

化学信息

分子量	384.41
分子式	C₁₄H₂₀N₆O₅S
CAS No.	979-92-0
Smiles	N[C@@H](CCSC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(N)ncnc12)C(O)=O
密度	1.91g/cm3

储存&溶解度

存储

store under nitrogen,store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

溶解度信息

DMSO: 63.1 mg/mL (164.15 mM), Sonication is recommended.

体内实验配方

10% DMSO+90% Saline: 12.5 mg/mL (32.52 mM), Solution.

请按顺序添加溶剂，在添加下一种溶剂之前，尽可能使溶液澄清。如有必要，可通过加热、超声、涡旋处理进行溶解。工作液建议现配现用。以上配方仅供参考，体内配方并不是绝对的，请根据不同情况进行调整。

溶液配制表

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.6014 mL	13.0069 mL	26.0139 mL	130.0695 mL
5 mM	0.5203 mL	2.6014 mL	5.2028 mL	26.0139 mL
10 mM	0.2601 mL	1.3007 mL	2.6014 mL	13.0069 mL
20 mM	0.1301 mL	0.6503 mL	1.3007 mL	6.5035 mL
50 mM	0.0520 mL	0.2601 mL	0.5203 mL	2.6014 mL
100 mM	0.0260 mL	0.1301 mL	0.2601 mL	1.3007 mL

体内实验配液计算器