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Anti-Phospho-p90RSK (Thr359, Ser363) Antibody (5P55)

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产品编号 TMAY-01715

Anti-Phospho-p90RSK (Thr359, Ser363) Antibody (5P55) 是一种 Rabbit 抗体,靶向 Phospho-p90RSK (Thr359, Ser363)。Anti-Phospho-p90RSK (Thr359, Ser363) Antibody (5P55) 可用于 WB。

Anti-Phospho-p90RSK (Thr359, Ser363) Antibody (5P55)

Anti-Phospho-p90RSK (Thr359, Ser363) Antibody (5P55)

Rating icon 还可以
产品编号 TMAY-01715

Anti-Phospho-p90RSK (Thr359, Ser363) Antibody (5P55) 是一种 Rabbit 抗体,靶向 Phospho-p90RSK (Thr359, Ser363)。Anti-Phospho-p90RSK (Thr359, Ser363) Antibody (5P55) 可用于 WB。

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产品介绍

生物活性
产品描述
Anti-Phospho-p90RSK (Thr359, Ser363) Antibody (5P55) is a Rabbit antibody targeting Phospho-p90RSK (Thr359, Ser363). Anti-Phospho-p90RSK (Thr359, Ser363) Antibody (5P55) can be used in WB.
Ig Type
Monoclonal Rabbit IgG
克隆号
5P55
交叉反应
Human
验证活性
1. Western blot analysis of extracts from serum-starved A431, untreated(line A) or treated with EGF (200ng/mL, 15min; +)(line B), using Phospho-p90RSK (Thr359, Ser363) rabbit monoclonal Antibody at 1:10000 dilution (upper) or Anti-Actin Antibody, Chimeric Rabbit Monoclonal at 1:50000 dilution (lower).

2. Western blot analysis of extracts from serum-starved A431, untreated (line A); treated with EGF (200ng/mL, 15min), without peptide (line B) or antigen-specific phosphopeptide (line C) or antigen-specific peptide (line D) using Phospho-p90RSK (Thr359, Ser363) rabbit monoclonal Antibody at 1:10000 dilution. (Validation Experiment)
应用
WB
推荐剂量
WB: 1:10000-1:100000
抗体种类
Monoclonal
宿主来源Rabbit
构建方式This antibody was obtained from a rabbit immunized with a synthetic peptide corresponding to the residues around (Thr359, Ser363) of Human p90RSK.
纯化方式Protein A
性状Liquid
缓冲液10 mM sodium HEPES, 150 mM NaCl, 100 μg/mL BSA, 50% glycerol, pH 7.5
研究背景RPS6KA1 (Ribosomal Protein S6 Kinase A1) is a Protein Coding gene. The RPS6KA1 gene, located on 1p36.11, is conserved in chimpanzee, Rhesus monkey, dog, cow, mouse, rat, chicken, zebrafish, C.elegans, and frog. This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 nonidentical kinase catalytic domains and phosphorylates various substrates, including members of the mitogen-activated kinase (MAPK) signaling pathway. The activity of this protein has been implicated in controlling cell growth and differentiation. RPS6KA1 is widely expressed in the small intestine, duodenum, and other tissues. Diseases associated with RPS6KA1 include Coffin-Lowry Syndrome and Tuberous Sclerosis. Among its related pathways are GDNF-Family Ligands and Receptor Interactions and NGF Pathway.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
A synthetic peptide corresponding to the residues around (Thr359, Ser363) of Human p90RSK
抗原种属
Human
存储&运输
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
运输方式Shipping with blue ice.

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